Literature DB >> 1116880

Specific inhibitory action of polyunsaturated fatty acids on lymphocyte transformation induced by PHA and PPD.

J Mertin, D Hughes.   

Abstract

Both saturated (SFA) and unsaturated fatty acids (UFS) inhibited PHA- and PPD-induced lymphocyte transformation. The degree of inhibition varied with the nature of the fatty acid (FA) and further comparison with their effect on unstimulated lymphocyte cultures suggests a specific action of polyunsaturated fatty acid (PUFA) on the lymphocyte PHA- and -PPD interaction. These findings are briefly discussed in the light of similar observations with PUFA-derived prostaglandins.

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Year:  1975        PMID: 1116880     DOI: 10.1159/000231306

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN: 0020-5915


  19 in total

1.  The in vitro effect of adrenergic agents and related compounds on triglyceride levels of guinea-pig lymphoid cells.

Authors:  S Kigoshi; R Ito
Journal:  Experientia       Date:  1976-02-15

Review 2.  Biologically active products from African Trypanosomes.

Authors:  I Tizard; K H Nielsen; J R Seed; J E Hall
Journal:  Microbiol Rev       Date:  1978-12

3.  The spleen is required for the suppression of experimental allergic encephalomyelitis by prostaglandin precursors.

Authors:  J Mertin; A Stackpoole
Journal:  Clin Exp Immunol       Date:  1979-06       Impact factor: 4.330

4.  Inhibition of host resistance by nutritional hypercholesteremia.

Authors:  W L Kos; R M Loria; M J Snodgrass; D Cohen; T G Thorpe; A M Kaplan
Journal:  Infect Immun       Date:  1979-11       Impact factor: 3.441

5.  Effect of dietary fats on the incidence of 7,12-dimethylbenz(a)-anthracene-induced tumors in rats.

Authors:  G J Hopkins; C E West; G C Hard
Journal:  Lipids       Date:  1976-04       Impact factor: 1.880

6.  The adjuvant activity of fatty acid esters. The role of acyl chain length and degree of saturation.

Authors:  R Bomford
Journal:  Immunology       Date:  1981-09       Impact factor: 7.397

7.  Influence of polyunsaturated fatty acids on survival of skin allografts and tumor incidence in mice.

Authors:  J Mertin; R Hunt
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

Review 8.  Effects of fatty acids on gap junctional communication: possible role in tumor promotion by dietary fat.

Authors:  C F Aylsworth; C W Welsch; J J Kabara; J E Trosko
Journal:  Lipids       Date:  1987-06       Impact factor: 1.880

9.  Increased proliferative response of lymphocytes from intestinal lymph during long chain fatty acid absorption.

Authors:  S Miura; H Imaeda; H Shiozaki; N Ohkubo; H Tashiro; H Serizawa; M Tsuchiya; P Tso
Journal:  Immunology       Date:  1993-01       Impact factor: 7.397

10.  Hemolytic factors in Schistosoma japonicum eggs.

Authors:  H Asahi; A Moribayashi; F Sendo; T Kobayakawa
Journal:  Infect Immun       Date:  1984-11       Impact factor: 3.441

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