Literature DB >> 11160115

The miaA mutator phenotype of Escherichia coli K-12 requires recombination functions.

J Zhao1, H E Leung, M E Winkler.   

Abstract

miaA mutants, which contain A-37 instead of the ms(2)i(6)A-37 hypermodification in their tRNA, show a moderate mutator phenotype leading to increased GC-->TA transversion. We show that the miaA mutator phenotype is dependent on recombination functions similar to, but not exactly the same as, those required for translation stress-induced mutagenesis.

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Year:  2001        PMID： 11160115      PMCID： PMC95069          DOI： 10.1128/JB.183.5.1796-1800.2001

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  32 in total

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Journal:  Mutat Res       Date:  1992-03       Impact factor: 2.433

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4.  Structure of Escherichia coli K-12 miaA and characterization of the mutator phenotype caused by miaA insertion mutations.

Authors:  D M Connolly; M E Winkler
Journal:  J Bacteriol       Date:  1991-03       Impact factor: 3.490

5.  Negative regulation of mutS and mutH repair gene expression by the Hfq and RpoS global regulators of Escherichia coli K-12.

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Authors:  M Escarceller; J Hicks; G Gudmundsson; G Trump; D Touati; S Lovett; P L Foster; K McEntee; M F Goodman
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10.  Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12.

Authors:  D M Connolly; M E Winkler
Journal:  J Bacteriol       Date:  1989-06       Impact factor: 3.490
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  8 in total

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