| Literature DB >> 11160015 |
P Robinson1, P C Okhuysen, C L Chappell, D E Lewis, I Shahab, A Janecki, A C White.
Abstract
Jejunal biopsies from volunteers challenged with Cryptosporidium parvum were examined for tumor necrosis factor alpha (TNF-alpha) and interleukin (IL)-1 beta mRNA. Postchallenge biopsies from 15 of 28 (54%) volunteers expressed TNF-alpha; 14% expressed IL-1 beta. Cytokine expression did not correlate with enteric symptoms, suggesting that TNF-alpha and IL-1 beta are not key mediators of diarrhea in human cryptosporidiosis.Entities:
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Year: 2001 PMID: 11160015 PMCID: PMC97999 DOI: 10.1128/IAI.69.2.1172-1174.2001
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441