Literature DB >> 11160015

Expression of tumor necrosis factor alpha and interleukin 1 beta in jejuna of volunteers after experimental challenge with Cryptosporidium parvum correlates with exposure but not with symptoms.

P Robinson1, P C Okhuysen, C L Chappell, D E Lewis, I Shahab, A Janecki, A C White.   

Abstract

Jejunal biopsies from volunteers challenged with Cryptosporidium parvum were examined for tumor necrosis factor alpha (TNF-alpha) and interleukin (IL)-1 beta mRNA. Postchallenge biopsies from 15 of 28 (54%) volunteers expressed TNF-alpha; 14% expressed IL-1 beta. Cytokine expression did not correlate with enteric symptoms, suggesting that TNF-alpha and IL-1 beta are not key mediators of diarrhea in human cryptosporidiosis.

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Year:  2001        PMID: 11160015      PMCID: PMC97999          DOI: 10.1128/IAI.69.2.1172-1174.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  24 in total

1.  Transforming growth factor beta1 is expressed in the jejunum after experimental Cryptosporidium parvum infection in humans.

Authors:  P Robinson; P C Okhuysen; C L Chappell; D E Lewis; I Shahab; S Lahoti; A C White
Journal:  Infect Immun       Date:  2000-09       Impact factor: 3.441

2.  Interferon-gamma expression in jejunal biopsies in experimental human cryptosporidiosis correlates with prior sensitization and control of oocyst excretion.

Authors:  A C White; P Robinson; P C Okhuysen; D E Lewis; I Shahab; S Lahoti; H L DuPont; C L Chappell
Journal:  J Infect Dis       Date:  2000-02       Impact factor: 5.226

3.  Lactulose-mannitol intestinal permeability test in children with diarrhea caused by rotavirus and cryptosporidium. Diarrhea Working Group, Peru.

Authors:  Y Zhang; B Lee; M Thompson; R Glass; R I Cama; D Figueroa; R Gilman; D Taylor; C Stephenson
Journal:  J Pediatr Gastroenterol Nutr       Date:  2000-07       Impact factor: 2.839

4.  Virulence of three distinct Cryptosporidium parvum isolates for healthy adults.

Authors:  P C Okhuysen; C L Chappell; J H Crabb; C R Sterling; H L DuPont
Journal:  J Infect Dis       Date:  1999-10       Impact factor: 5.226

5.  Glutamine stimulates prostaglandin-sensitive Na(+)-H+ exchange in experimental porcine cryptosporidiosis.

Authors:  R A Argenzio; J M Rhoads; M Armstrong; G Gomez
Journal:  Gastroenterology       Date:  1994-06       Impact factor: 22.682

6.  Intensity of infection in AIDS-associated cryptosporidiosis.

Authors:  R W Goodgame; R M Genta; A C White; C L Chappell
Journal:  J Infect Dis       Date:  1993-03       Impact factor: 5.226

7.  Villous atrophy, crypt hyperplasia, cellular infiltration, and impaired glucose-Na absorption in enteric cryptosporidiosis of pigs.

Authors:  R A Argenzio; J A Liacos; M L Levy; D J Meuten; J G Lecce; D W Powell
Journal:  Gastroenterology       Date:  1990-05       Impact factor: 22.682

8.  Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

Authors:  J L Madara; J Stafford
Journal:  J Clin Invest       Date:  1989-02       Impact factor: 14.808

9.  Prostanoids inhibit intestinal NaCl absorption in experimental porcine cryptosporidiosis.

Authors:  R A Argenzio; J Lecce; D W Powell
Journal:  Gastroenterology       Date:  1993-02       Impact factor: 22.682

10.  Enterotoxic effect of stool supernatant of Cryptosporidium-infected calves on human jejunum.

Authors:  A Guarino; R B Canani; E Pozio; L Terracciano; F Albano; M Mazzeo
Journal:  Gastroenterology       Date:  1994-01       Impact factor: 22.682

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  10 in total

1.  Role of tumor necrosis factor alpha in development of immunity against Cryptosporidium parvum infection.

Authors:  I-Sarah Lean; Sonia Lacroix-Lamandé; Fabrice Laurent; Vincent McDonald
Journal:  Infect Immun       Date:  2006-07       Impact factor: 3.441

Review 2.  Intestinal immune response to human Cryptosporidium sp. infection.

Authors:  Birte Pantenburg; Sara M Dann; Heuy-Ching Wang; Prema Robinson; Alejandro Castellanos-Gonzalez; Dorothy E Lewis; A Clinton White
Journal:  Infect Immun       Date:  2007-10-29       Impact factor: 3.441

Review 3.  Human immune responses in cryptosporidiosis.

Authors:  Anoli Borad; Honorine Ward
Journal:  Future Microbiol       Date:  2010-03       Impact factor: 3.165

4.  Identification and immunological characterization of three potential vaccinogens against Cryptosporidium species.

Authors:  Patricio A Manque; Fernando Tenjo; Ute Woehlbier; Ana M Lara; Myrna G Serrano; Ping Xu; João M Alves; Ronald B Smeltz; Daniel H Conrad; Gregory A Buck
Journal:  Clin Vaccine Immunol       Date:  2011-09-14

Review 5.  The cell biology of cryptosporidium infection.

Authors:  Steven P O'Hara; Xian-Ming Chen
Journal:  Microbes Infect       Date:  2011-03-31       Impact factor: 2.700

6.  The Efficacy of Citrus maxima Peels Aqueous Extract Against Cryptosporidiosis in Immunecompromised Mice.

Authors:  Eman Naser Hafez; Wafaa Fayez Abd El Hamed
Journal:  Acta Parasitol       Date:  2021-01-20       Impact factor: 1.440

7.  Differential regulation of beta-defensin gene expression during Cryptosporidium parvum infection.

Authors:  Tarek K Zaalouk; Mona Bajaj-Elliott; John T George; Vincent McDonald
Journal:  Infect Immun       Date:  2004-05       Impact factor: 3.441

8.  Cryptosporidiosis-an overview.

Authors:  Gordon J Leitch; Qing He
Journal:  J Biomed Res       Date:  2012-02-21

9.  A rapid IL-17 response to Cryptosporidium parvum in the bovine intestine.

Authors:  Emma Drinkall; Matthew J Wass; Tracey J Coffey; Robin J Flynn
Journal:  Vet Immunol Immunopathol       Date:  2017-07-23       Impact factor: 2.046

10.  Pathogenicity of Cryptosporidium parvum--evaluation of an animal infection model.

Authors:  H L Enemark; V Bille-Hansen; P Lind; P M H Heegaard; H Vigre; P Ahrens; S M Thamsborg
Journal:  Vet Parasitol       Date:  2003-04-02       Impact factor: 2.738

  10 in total

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