Literature DB >> 11147389

The epidemic of Alzheimer's disease. How can we manage the costs?

N Johnson1, T Davis, N Bosanquet.   

Abstract

Alzheimer's disease is one of several diseases of the elderly that has recently come into prominence for a number of reasons. First, its prevalence is set to increase as a result of the aging of Western populations. Secondly, the use of institutional care has fallen as a result of major policy changes in many countries, and this has caused a shift in the pattern of care for the elderly. Finally, the advent of innovative pharmacotherapy has caused third-party payers and clinicians to question the way in which this disease is best managed. International epidemiological data for Western populations point to a potentially considerable increase in the prevalence of the disease over the next 2 decades. Although the cost estimates of the disease vary widely among, or indeed, within different Western countries, they may be considerable. It is clear that innovative strategies, e.g. the use of respite care, sheltered housing and pharmacotherapy, might serve to limit the amount of time patients spend in institutional care. Even a small reduction in this form of care might be sufficient to offset the costs of treatment. What is lacking today are clear demonstrations as to how these new strategies might contribute to the overall management of this complex and multifactorial disease: this should be the joint focus of care providers and the pharmaceutical industry in the near future.

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Year:  2000        PMID: 11147389     DOI: 10.2165/00019053-200018030-00002

Source DB:  PubMed          Journal:  Pharmacoeconomics        ISSN: 1170-7690            Impact factor:   4.981


  18 in total

1.  Alzheimer's disease care: costs and potential savings.

Authors:  J Leon; C K Cheng; P J Neumann
Journal:  Health Aff (Millwood)       Date:  1998 Nov-Dec       Impact factor: 6.301

2.  Economic impact of Alzheimer's disease in the United Kingdom. Cost of care and disease severity for non-institutionalised patients with Alzheimer's disease.

Authors:  E Souêtre; R M Thwaites; H L Yeardley
Journal:  Br J Psychiatry       Date:  1999-01       Impact factor: 9.319

Review 3.  Donepezil. Pharmacoeconomic implications of therapy.

Authors:  R H Foster; G L Plosker
Journal:  Pharmacoeconomics       Date:  1999-07       Impact factor: 4.981

Review 4.  Economic considerations in Alzheimer's disease.

Authors:  P D Meek; K McKeithan; G T Schumock
Journal:  Pharmacotherapy       Date:  1998 Mar-Apr       Impact factor: 4.705

5.  Economic evaluation of donepezil for the treatment of Alzheimer's disease in Canada.

Authors:  B J O'Brien; R Goeree; M Hux; M Iskedjian; G Blackhouse; M Gagnon; S Gauthier
Journal:  J Am Geriatr Soc       Date:  1999-05       Impact factor: 5.562

Review 6.  Economic research on Alzheimer disease: a review of the literature.

Authors:  R L Ernst; J W Hay
Journal:  Alzheimer Dis Assoc Disord       Date:  1997       Impact factor: 2.703

7.  The economic and social burden of Alzheimer disease on families in the Lombardy region of Italy.

Authors:  M C Cavallo; G Fattore
Journal:  Alzheimer Dis Assoc Disord       Date:  1997-12       Impact factor: 2.703

8.  Frequency and distribution of Alzheimer's disease in Europe: a collaborative study of 1980-1990 prevalence findings. The EURODEM-Prevalence Research Group.

Authors:  W A Rocca; A Hofman; C Brayne; M M Breteler; M Clarke; J R Copeland; J F Dartigues; K Engedal; O Hagnell; T J Heeren
Journal:  Ann Neurol       Date:  1991-09       Impact factor: 10.422

9.  Canadian study of health and aging: study methods and prevalence of dementia.

Authors: 
Journal:  CMAJ       Date:  1994-03-15       Impact factor: 8.262

10.  Relation between severity of Alzheimer's disease and costs of caring.

Authors:  M J Hux; B J O'Brien; M Iskedjian; R Goeree; M Gagnon; S Gauthier
Journal:  CMAJ       Date:  1998-09-08       Impact factor: 8.262

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  18 in total

1.  Assessing the health and economic impact of galantamine treatment in patients with Alzheimer's disease in the health care systems of different countries.

Authors:  Jaime Caro; Maribel Salas; Alexandra Ward; Denis Getsios; Kristen Migliaccio-Walle; Frances Garfield
Journal:  Drugs Aging       Date:  2004       Impact factor: 3.923

Review 2.  The ART of loss: Abeta imaging in the evaluation of Alzheimer's disease and other dementias.

Authors:  Victor L Villemagne; Michelle T Fodero-Tavoletti; Kerryn E Pike; Roberto Cappai; Colin L Masters; Christopher C Rowe
Journal:  Mol Neurobiol       Date:  2008-08-09       Impact factor: 5.590

Review 3.  Nanoparticle-mediated brain-specific drug delivery, imaging, and diagnosis.

Authors:  Hu Yang
Journal:  Pharm Res       Date:  2010-07-01       Impact factor: 4.200

Review 4.  Rivastigmine. A pharmacoeconomic review of its use in Alzheimer's disease.

Authors:  H M Lamb; K L Goa
Journal:  Pharmacoeconomics       Date:  2001       Impact factor: 4.981

5.  Galantamine: a pharmacoeconomic review of its use in Alzheimer's disease.

Authors:  Katherine A Lyseng-Williamson; Greg L Plosker
Journal:  Pharmacoeconomics       Date:  2002       Impact factor: 4.981

Review 6.  Memantine: a review of its use in Alzheimer's disease.

Authors:  Dean M Robinson; Gillian M Keating
Journal:  Drugs       Date:  2006       Impact factor: 9.546

Review 7.  Memantine: a pharmacoeconomic review of its use in moderate-to-severe Alzheimer's disease.

Authors:  Greg L Plosker; Katherine A Lyseng-Williamson
Journal:  Pharmacoeconomics       Date:  2005       Impact factor: 4.981

8.  Causes of syncope in patients with Alzheimer's disease treated with donepezil.

Authors:  Philippe Bordier; Stephane Lanusse; Stephane Garrigue; Charlotte Reynard; Frederic Robert; Laurent Gencel; Alexia Lafitte
Journal:  Drugs Aging       Date:  2005       Impact factor: 3.923

9.  Intelligent assistive technology applications to dementia care: current capabilities, limitations, and future challenges.

Authors:  Ashok J Bharucha; Vivek Anand; Jodi Forlizzi; Mary Amanda Dew; Charles F Reynolds; Scott Stevens; Howard Wactlar
Journal:  Am J Geriatr Psychiatry       Date:  2009-02       Impact factor: 4.105

10.  Time Trends in the Prevalence of Neurocognitive Disorders and Cognitive Impairment in the United States: The Effects of Disease Severity and Improved Ascertainment.

Authors:  Igor Akushevich; Arseniy P Yashkin; Julia Kravchenko; Svetlana Ukraintseva; Eric Stallard; Anatoliy I Yashin
Journal:  J Alzheimers Dis       Date:  2018       Impact factor: 4.472

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