Literature DB >> 11146126

Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus.

P J Kenny1, S E File, M Rattray.   

Abstract

Acute nicotine administration (0.5 mg/kg i.p.) significantly decreased BDNF mRNA levels in dentate gyrus, CA3 and CA1 subfields of the rat hippocampus 2 h and 24 h after administration. However, with 7 days nicotine treatment, tolerance developed to the inhibitory effect of nicotine on BDNF mRNA expression and there was a significant increase in BDNF expression 2 h after the final injection in the CA1 region. These data suggests that changes in expression of hippocampal BDNF may be involved in the behavioural effects of nicotine observed after acute and chronic treatment.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 11146126     DOI： 10.1016/s0169-328x(00)00246-1

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN： 0169-328X


  43 in total

1.  Chronic fluoxetine ameliorates adolescent chronic nicotine exposure-induced long-term adult deficits in trace conditioning.

Authors:  David A Connor; Thomas J Gould
Journal:  Neuropharmacology       Date:  2017-08-02       Impact factor: 5.250

2.  Substance abuse may be a risk factor for earlier onset of Huntington disease.

Authors:  Joanne A Byars; Leigh J Beglinger; David J Moser; Pedro Gonzalez-Alegre; Peg Nopoulos
Journal:  J Neurol       Date:  2012-01-25       Impact factor: 4.849

Review 3.  Cellular events in nicotine addiction.

Authors:  Rachel E Penton; Robin A J Lester
Journal:  Semin Cell Dev Biol       Date:  2009-01-20       Impact factor: 7.727

4.  Impact of prenatal exposure to cocaine and tobacco on diffusion tensor imaging and sensation seeking in adolescents.

Authors:  Jie Liu; Ronald A Cohen; Assawin Gongvatana; Stephen J Sheinkopf; Barry M Lester
Journal:  J Pediatr       Date:  2011-07-02       Impact factor: 4.406

5.  Effects of cigarette smoking and alcohol use on neurocognition and BDNF levels in a Chinese population.

Authors:  Xiang Yang Zhang; Yun-Long Tan; Da-Chun Chen; Shu-Ping Tan; Fu-De Yang; Giovana B Zunta-Soares; Jair C Soares
Journal:  Psychopharmacology (Berl)       Date:  2015-10-30       Impact factor: 4.530

Review 6.  Estrogen-BDNF interactions: implications for neurodegenerative diseases.

Authors:  Farida Sohrabji; Danielle K Lewis
Journal:  Front Neuroendocrinol       Date:  2006-10-27       Impact factor: 8.606

7.  Promoter IV-BDNF deficiency disturbs cholinergic gene expression of CHRNA5, CHRM2, and CHRM5: effects of drug and environmental treatments.

Authors:  Kazuko Sakata; Abigail E Overacre
Journal:  J Neurochem       Date:  2017-08-16       Impact factor: 5.372

8.  Nicotine restores Wt-like levels of reelin and GAD67 gene expression in brain of heterozygous reeler mice.

Authors:  Emilia Romano; Andrea Fuso; Giovanni Laviola
Journal:  Neurotox Res       Date:  2013-02-06       Impact factor: 3.911

Review 9.  Molecular and genetic substrates linking stress and addiction.

Authors:  Lisa A Briand; Julie A Blendy
Journal:  Brain Res       Date:  2009-11-10       Impact factor: 3.252

Review 10.  Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice.

Authors:  Christie D Fowler; Michael A Arends; Paul J Kenny
Journal:  Behav Pharmacol       Date:  2008-09       Impact factor: 2.293
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.