Literature DB >> 11144114

Interleukin-1 family: from genes to human disease.

B Laurincová1.   

Abstract

Interleukin-1 (IL-1) is one of the most potent proinflammatory cytokines involved both in physiological immune responses and in the development of various immunopathological disorders. The members of IL-1 family form a complex system with tight regulatory mechanisms and clarifying their role in disease remains in the centre of research interests. This review article except of summarising recent findings about IL-1 family members focuses on associations of IL-1 gene complex polymorphisms with human diseases.

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Year:  2000        PMID： 11144114

Source DB:  PubMed          Journal:  Acta Univ Palacki Olomuc Fac Med        ISSN： 0301-2514


  6 in total

1.  TNFRSF10B polymorphisms and haplotypes associated with increased risk of death in non-small cell lung cancer.

Authors:  Matthew B Schabath; Anna R Giuliano; Zachary J Thompson; Ernest K Amankwah; Jhanelle E Gray; David A Fenstermacher; Kristen A Jonathan; Amer A Beg; Eric B Haura
Journal:  Carcinogenesis       Date:  2013-07-09       Impact factor: 4.944

2.  Environmental factors and not genotype influence the plasma level of interleukin-1 receptor antagonist in normal individuals.

Authors:  H Cullup; P G Middleton; G Duggan; J S Conn; A M Dickinson
Journal:  Clin Exp Immunol       Date:  2004-08       Impact factor: 4.330

3.  The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis.

Authors:  Andrew E Timms; Alison M Crane; Anne-Marie Sims; Heather J Cordell; Linda A Bradbury; Aaron Abbott; Mark R E Coyne; Owen Beynon; Ibi Herzberg; Gordon W Duff; Andrei Calin; Lon R Cardon; B Paul Wordsworth; Matthew A Brown
Journal:  Am J Hum Genet       Date:  2004-08-12       Impact factor: 11.025

4.  Innate immunity: a cutaneous perspective.

Authors:  Heidi Goodarzi; Janet Trowbridge; Richard L Gallo
Journal:  Clin Rev Allergy Immunol       Date:  2007-10       Impact factor: 10.817

5.  Association of IL1 beta gene polymorphism and allograft functions in renal transplant recipients :a case control study from Kashmir Valley.

Authors:  Mohammad Ashraf Bhat; Manzoor Ahmad Parry; Saniya Nissar; Aga Syed Sameer; Imtiyaz A Bhat; Zafar A Shah; Roohi Rasool
Journal:  BMC Nephrol       Date:  2017-03-30       Impact factor: 2.388

6.  Associations between IL-1RN variable number of tandem repeat, IL-1β (-511) and IL-1β (+3954) gene polymorphisms and urolithiasis in Uighur children of China.

Authors:  Jiefeng Xiao; Shukai Zheng; Zhaolong Qiu; Kusheng Wu
Journal:  Asian J Urol       Date:  2021-05-03
  6 in total

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