OBJECTIVE: Performance IQ (PIQ) is often lower than verbal IQ (VIQ) in schizophrenic patients. Whether PIQ < VIQ precedes psychotic symptoms in schizophrenia remains uncertain. METHOD: We investigated premorbid IQ scores in 63 subjects assessed at a child and adolescent psychiatric unit (mean age 13.1 years, SD 3.2), who at follow-up in adulthood (mean age 30.9 years, SD 3.9) received a lifetime RDC diagnosis of schizophrenia-related psychosis, affective disorder, or no psychiatric disorder. RESULTS: Premorbid PIQ < VIQ significantly differentiated the groups with schizophrenia-related psychosis and no psychiatric disorder. Subjects with schizophrenia-related psychosis had a significantly lower mean value for premorbid PIQ, but not VIQ, compared to subjects who developed affective disorder or subjects without psychiatric disorder. CONCLUSION: Our results emphasize premorbid intellectual deficits in schizophrenia. Those deficits might largely be in consequence of an impairment on the PIQ scale.
OBJECTIVE:Performance IQ (PIQ) is often lower than verbal IQ (VIQ) in schizophrenicpatients. Whether PIQ < VIQ precedes psychotic symptoms in schizophrenia remains uncertain. METHOD: We investigated premorbid IQ scores in 63 subjects assessed at a child and adolescent psychiatric unit (mean age 13.1 years, SD 3.2), who at follow-up in adulthood (mean age 30.9 years, SD 3.9) received a lifetime RDC diagnosis of schizophrenia-related psychosis, affective disorder, or no psychiatric disorder. RESULTS: Premorbid PIQ < VIQ significantly differentiated the groups with schizophrenia-related psychosis and no psychiatric disorder. Subjects with schizophrenia-related psychosis had a significantly lower mean value for premorbid PIQ, but not VIQ, compared to subjects who developed affective disorder or subjects without psychiatric disorder. CONCLUSION: Our results emphasize premorbid intellectual deficits in schizophrenia. Those deficits might largely be in consequence of an impairment on the PIQ scale.
Authors: Maria Mattsson; Lena Flyckt; Gunnar Edman; Håkan Nyman; Johan Cullberg; Yvonne Forsell Journal: Int J Methods Psychiatr Res Date: 2007 Impact factor: 4.035
Authors: Holger J Sørensen; Erik L Mortensen; Jason Schiffman; Morten Ekstrøm; Danielle Denenney; Sarnoff A Mednick Journal: Psychiatry Res Date: 2010-05-05 Impact factor: 3.222
Authors: Chelsea Lowther; Daniele Merico; Gregory Costain; Jack Waserman; Kerry Boyd; Abdul Noor; Marsha Speevak; Dimitri J Stavropoulos; John Wei; Anath C Lionel; Christian R Marshall; Stephen W Scherer; Anne S Bassett Journal: Genome Med Date: 2017-11-30 Impact factor: 11.117