| Literature DB >> 11140732 |
N J Lawrence1, D Rennison, M Woo, A T McGown, J A Hadfield.
Abstract
A series of diarylamines, diaryl and arylbenzyl ethers based on combretastatin A-4 was prepared and evaluated for anticancer activity. 2-Methoxy-5-(3',4',5'-trimethoxyphenoxymethyl)phenol was the most active (IC50, K562 20 nM) and caused significant G2/M cell cycle arrest.Entities:
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Year: 2001 PMID： 11140732 DOI： 10.1016/s0960-894x(00)00596-5
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823