| Literature DB >> 11137030 |
Abstract
Recent genetic studies in Drosophila and mouse have uncovered a new aspect of the Wnt signal transduction machinery. Mutations disrupting LDL-receptor related proteins produce loss-of-function Wnt phenotypes, suggesting that these cell surface molecules may represent essential co-receptors for Wnt ligands.Entities:
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Year: 2000 PMID: 11137030 DOI: 10.1016/s0960-9822(00)00852-6
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834