Literature DB >> 11133709

Sensitivity and specificity of a new scoring system for diabetic macular oedema detection using a confocal laser imaging system.

L Tong1, A Ang, S A Vernon, H J Zambarakji, A Bhan, V Sung, S Page.   

Abstract

AIM: To assess the use of the Heidelberg retina tomograph (HRT) in screening for sight threatening diabetic macular oedema in a hospital diabetic clinic, using a new subjective analysis system (SCORE).
METHODS: 200 eyes of 100 consecutive diabetic patients attending a diabetologist's clinic were studied, all eyes had an acuity of 6/9 or better. All patients underwent clinical examination by an ophthalmologist. Using the HRT, one good scan was obtained for each eye centred on the fovea. A System for Classification and Ordering of Retinal Edema (SCORE) was developed using subjective assessment of the colour map and the reflectivity image. The interobserver agreement of using this method to detect macular oedema was assessed by two observers (ophthalmic trainees) who were familiarized with SCORE by studying standard pictures of eyes not in the study. All scans were graded from 0-6 and test positive cases were defined as having a SCORE value of 0-2. The sensitivity of SCORE was assessed by pooling the data with an additional 88 scans of 88 eyes in order to reduce the confidence interval of the index.
RESULTS: 12 eyes in eight out of the 100 patients had macular oedema clinically. Three scans in three patients could not be analysed because of poor scan quality. In the additional group of scans 76 out of 88 eyes had macular oedema clinically. The scoring system had a specificity of 99% (95% CI 96-100) and sensitivity of 67% (95% CI 57-76). The predictive value of a negative test was 87% (95% CI 82-99), and that of a positive test was 95% (95% CI 86-99). The mean difference of the SCORE value between two observers was -0.2 (95% CI -0.5 to +0.07).
CONCLUSIONS: These data suggest that SCORE is potentially useful for detecting diabetic macular oedema in hospital diabetic patients.

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Mesh:

Year:  2001        PMID: 11133709      PMCID: PMC1723671          DOI: 10.1136/bjo.85.1.34

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  13 in total

1.  Assessment of non-mydriatic fundus photography in detection of diabetic retinopathy.

Authors:  R Williams; S Nussey; R Humphry; G Thompson
Journal:  Br Med J (Clin Res Ed)       Date:  1986-11-01

2.  Clinical grading and the effects of scaling.

Authors:  I L Bailey; M A Bullimore; T W Raasch; H R Taylor
Journal:  Invest Ophthalmol Vis Sci       Date:  1991-02       Impact factor: 4.799

3.  Assessment of the Heidelberg Retina Tomograph in the detection of sight-threatening diabetic maculopathy.

Authors:  H J Zambarakji; T K Butler; S A Vernon
Journal:  Eye (Lond)       Date:  1999-04       Impact factor: 3.775

4.  Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Early Treatment Diabetic Retinopathy Study Research Group.

Authors: 
Journal:  Ophthalmology       Date:  1991-05       Impact factor: 12.079

5.  Comparison between an ophthalmic optician and an ophthalmologist in screening for diabetic retinopathy.

Authors:  C J Hammond; J Shackleton; D W Flanagan; J Herrtage; J Wade
Journal:  Eye (Lond)       Date:  1996       Impact factor: 3.775

6.  Comparison of non-mydriatic retinal photography with ophthalmoscopy in 2159 patients: mobile retinal camera study.

Authors:  R Taylor; L Lovelock; W M Tunbridge; K G Alberti; R G Brackenridge; P Stephenson; E Young
Journal:  BMJ       Date:  1990-12-01

7.  Diagnosis of diabetic eye disease.

Authors:  E J Sussman; W G Tsiaras; K A Soper
Journal:  JAMA       Date:  1982-06-18       Impact factor: 56.272

8.  Screening of diabetics for retinopathy by ophthalmic opticians.

Authors:  C J Burns-Cox; J C Hart
Journal:  Br Med J (Clin Res Ed)       Date:  1985-04-06

9.  Adding retinal photography to screening for diabetic retinopathy: a prospective study in primary care.

Authors:  J P O'Hare; A Hopper; C Madhaven; M Charny; T S Purewell; B Harney; J Griffiths
Journal:  BMJ       Date:  1996-03-16

10.  Sensitivity and specificity of photography and direct ophthalmoscopy in screening for sight threatening eye disease: the Liverpool Diabetic Eye Study.

Authors:  S P Harding; D M Broadbent; C Neoh; M C White; J Vora
Journal:  BMJ       Date:  1995-10-28
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  1 in total

1.  [Measurement of retinal thickness with the Heidelberg retina tomograph for patients with macular edema and healthy individuals].

Authors:  A Ackermann; L E Pillunat
Journal:  Ophthalmologe       Date:  2012-09       Impact factor: 1.059

  1 in total

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