Literature DB >> 11122769

Genetics of atherosclerosis: the search for genes acting at the level of the vessel wall.

V Villa-Colinayo1, W Shi, J Araujo, A J Lusis.   

Abstract

Recent studies in mice have revealed genetic factors contributing to atherosclerosis that are independent of known risk factors. These factors appear to act locally, at the level of the vessel wall. In this review, we discuss these studies and summarize some of the cellular and molecular interactions that may be involved. We also outline the approaches for the identification of such factors in humans.

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Year:  2000        PMID： 11122769     DOI： 10.1007/s11883-000-0076-2

Source DB:  PubMed          Journal:  Curr Atheroscler Rep        ISSN： 1523-3804            Impact factor:   5.113


  55 in total

1.  Determinants of atherosclerosis susceptibility in the C3H and C57BL/6 mouse model: evidence for involvement of endothelial cells but not blood cells or cholesterol metabolism.

Authors:  W Shi; N J Wang; D M Shih; V Z Sun; X Wang; A J Lusis
Journal:  Circ Res       Date:  2000-05-26       Impact factor: 17.367

2.  Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group.

Authors:  D H O'Leary; J F Polak; R A Kronmal; T A Manolio; G L Burke; S K Wolfson
Journal:  N Engl J Med       Date:  1999-01-07       Impact factor: 91.245

3.  Requirement for CD154 in the progression of atherosclerosis.

Authors:  E Lutgens; L Gorelik; M J Daemen; E D de Muinck; I S Grewal; V E Koteliansky; R A Flavell
Journal:  Nat Med       Date:  1999-11       Impact factor: 53.440

4.  Noninvasive determination of endothelium-mediated vasodilation as a screening test for coronary artery disease: pilot study to assess the predictive value in comparison with angina pectoris, exercise electrocardiography, and myocardial perfusion imaging.

Authors:  S Schroeder; M D Enderle; R Ossen; C Meisner; A Baumbach; M Pfohl; C Herdeg; M Oberhoff; H U Haering; K R Karsch
Journal:  Am Heart J       Date:  1999-10       Impact factor: 4.749

5.  IFN-gamma potentiates atherosclerosis in ApoE knock-out mice.

Authors:  S Gupta; A M Pablo; X c Jiang; N Wang; A R Tall; C Schindler
Journal:  J Clin Invest       Date:  1997-06-01       Impact factor: 14.808

6.  Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression.

Authors:  S Ye; P Eriksson; A Hamsten; M Kurkinen; S E Humphries; A M Henney
Journal:  J Biol Chem       Date:  1996-05-31       Impact factor: 5.157

7.  Thermal heterogeneity within human atherosclerotic coronary arteries detected in vivo: A new method of detection by application of a special thermography catheter.

Authors:  C Stefanadis; L Diamantopoulos; C Vlachopoulos; E Tsiamis; J Dernellis; K Toutouzas; E Stefanadi; P Toutouzas
Journal:  Circulation       Date:  1999-04-20       Impact factor: 29.690

8.  C-Reactive protein and coronary artery disease: additional evidence of the implication of an inflammatory process in acute coronary syndromes.

Authors:  I Abdelmouttaleb; N Danchin; C Ilardo; I Aimone-Gastin; M Angioï; A Lozniewski; J Loubinoux; A Le Faou; J L Guéant
Journal:  Am Heart J       Date:  1999-02       Impact factor: 4.749

9.  Association of variables of coagulation, fibrinolysis and acute-phase with atherosclerosis in coronary and peripheral arteries and those arteries supplying the brain.

Authors:  J Heinrich; H Schulte; R Schönfeld; E Köhler; G Assmann
Journal:  Thromb Haemost       Date:  1995-03       Impact factor: 5.249

10.  Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

Authors:  Z S Galis; G K Sukhova; M W Lark; P Libby
Journal:  J Clin Invest       Date:  1994-12       Impact factor: 14.808
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