Literature DB >> 11120989

Nitrofurantoin is active against vancomycin-resistant enterococci.

G G Zhanel1, D J Hoban, J A Karlowsky.   

Abstract

The activity of nitrofurantoin was tested against 300 isolates of Enterococcus faecium, Enterococcus faecalis, and Enterococcus gallinarum. No isolates tested were resistant to nitrofurantoin (MIC, >/=128 microg/ml), including vancomycin-resistant E. faecium isolates with vanA- and vanB-positive genotypes and vancomycin-resistant E. gallinarum isolates. We conclude that nitrofurantoin may provide effective treatment of urinary tract infections caused by vancomycin-resistant enterococci.

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Year:  2001        PMID: 11120989      PMCID: PMC90284          DOI: 10.1128/AAC.45.1.324-326.2001

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  14 in total

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6.  Treatment of vancomycin-resistant Enterococcus faecium infections.

Authors:  K K Lai
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Review 7.  The pharmacokinetics of nitrofurantoin and its related bioavailability.

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9.  Antimicrobial activity of quinupristin-dalfopristin (RP 59500, Synercid) tested against over 28,000 recent clinical isolates from 200 medical centers in the United States and Canada.

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Journal:  Diagn Microbiol Infect Dis       Date:  1998-07       Impact factor: 2.803

10.  Screening of stool samples for identification of vancomycin-resistant Enterococcus isolates should include the methyl-alpha-D-glucopyranoside test to differentiate nonmotile Enterococcus gallinarum from E. faecium.

Authors:  C Y Turenne; D J Hoban; J A Karlowsky; G G Zhanel; A M Kabani
Journal:  J Clin Microbiol       Date:  1998-08       Impact factor: 5.948

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