Literature DB >> 11113924

Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method.

G Xu1, H R Schmid, X Lu, H M Liebich, P Lu.   

Abstract

Modified nucleosides, formed post-transcriptionally in RNA by a number of modification enzymes, are excreted in abnormal levels in the urine of patients with malignant tumors. To test their usefulness as tumor markers, and to compare them with the conventional tumor markers, a reversed-phase high-performance liquid chromatographic (RP-HPLC) method and a factor analysis method have been used to study the excretion pattern of nucleosides of breast cancer patients. A clear cut differentiation of the breast cancer group and the healthy individuals in two clusters without overlapping was obtained. Copyright 2000 John Wiley & Sons, Ltd.

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Year:  2000        PMID： 11113924     DOI： 10.1002/1099-0801(200011)14:7<459::AID-BMC7>3.0.CO;2-K

Source DB:  PubMed          Journal:  Biomed Chromatogr        ISSN： 0269-3879            Impact factor:   1.902


  10 in total

1.  Urinary nucleosides as biological markers for patients with colorectal cancer.

Authors:  Yu-Fang Zheng; Jun Yang; Xin-Jie Zhao; Bo Feng; Hong-Wei Kong; Ying-Jie Chen; Shen Lv; Min-Hua Zheng; Guo-Wang Xu
Journal:  World J Gastroenterol       Date:  2005-07-07       Impact factor: 5.742

Review 2.  Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids.

Authors:  Joana Krämer; Rui Kang; Laura M Grimm; Luisa De Cola; Pierre Picchetti; Frank Biedermann
Journal:  Chem Rev       Date:  2022-01-07       Impact factor: 60.622

3.  Expression and significance of m1A transmethylase, hTrm6p/hTrm61p and its related gene hTrm6/hTrm61 in bladder urothelial carcinoma.

Authors:  Lei Shi; Xiao-Ming Yang; Dong-Dong Tang; Gang Liu; Pu Yuan; Yang Yang; Lian-Sheng Chang; Li-Rong Zhang; Dong-Kui Song
Journal:  Am J Cancer Res       Date:  2015-06-15       Impact factor: 6.166

4.  Noninvasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer.

Authors:  Ewy A Mathé; Andrew D Patterson; Majda Haznadar; Soumen K Manna; Kristopher W Krausz; Elise D Bowman; Peter G Shields; Jeffrey R Idle; Philip B Smith; Katsuhiro Anami; Dickran G Kazandjian; Emmanuel Hatzakis; Frank J Gonzalez; Curtis C Harris
Journal:  Cancer Res       Date:  2014-04-15       Impact factor: 12.701

5.  Identification of urinary modified nucleosides and ribosylated metabolites in humans via combined ESI-FTICR MS and ESI-IT MS analysis.

Authors:  Dino Bullinger; Richard Fux; Graeme Nicholson; Stefan Plontke; Claus Belka; Stefan Laufer; Christoph H Gleiter; Bernd Kammerer
Journal:  J Am Soc Mass Spectrom       Date:  2008-06-28       Impact factor: 3.109

6.  Conformational change in transfer RNA is an early indicator of acute cellular damage.

Authors:  Eikan Mishima; Chisako Inoue; Daisuke Saigusa; Ryusuke Inoue; Koki Ito; Yusuke Suzuki; Daisuke Jinno; Yuri Tsukui; Yosuke Akamatsu; Masatake Araki; Kimi Araki; Ritsuko Shimizu; Haruka Shinke; Takehiro Suzuki; Yoichi Takeuchi; Hisato Shima; Yasutoshi Akiyama; Takafumi Toyohara; Chitose Suzuki; Yoshikatu Saiki; Teiji Tominaga; Shigehito Miyagi; Naoki Kawagisihi; Tomoyoshi Soga; Takayoshi Ohkubo; Kenichi Yamamura; Yutaka Imai; Satohiro Masuda; Venkata Sabbisetti; Takaharu Ichimura; David B Mount; Joseph V Bonventre; Sadayoshi Ito; Yoshihisa Tomioka; Kunihiko Itoh; Takaaki Abe
Journal:  J Am Soc Nephrol       Date:  2014-05-15       Impact factor: 10.121

Review 7.  The state-of-the-art determination of urinary nucleosides using chromatographic techniques "hyphenated" with advanced bioinformatic methods.

Authors:  Wiktoria Struck; Małgorzata Waszczuk-Jankowska; Roman Kaliszan; Michał J Markuszewski
Journal:  Anal Bioanal Chem       Date:  2011-02-27       Impact factor: 4.142

8.  Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control.

Authors:  A Seidel; S Brunner; P Seidel; G I Fritz; O Herbarth
Journal:  Br J Cancer       Date:  2006-06-05       Impact factor: 7.640

9.  Exometabolom analysis of breast cancer cell lines: Metabolic signature.

Authors:  Lucas Willmann; Thalia Erbes; Sebastian Halbach; Tilman Brummer; Markus Jäger; Marc Hirschfeld; Tanja Fehm; Hans Neubauer; Elmar Stickeler; Bernd Kammerer
Journal:  Sci Rep       Date:  2015-08-21       Impact factor: 4.379

Review 10.  Role of Urinary Biomarkers in the Diagnosis of Adenoma and Colorectal Cancer: A Systematic Review and Meta-Analysis.

Authors:  Emma Altobelli; Paolo Matteo Angeletti; Giovanni Latella
Journal:  J Cancer       Date:  2016-10-08       Impact factor: 4.207
  10 in total

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