Literature DB >> 11104561

Screening breast cancer patients for Norwegian ATM mutations.

K Laake1, P Vu, T I Andersen, B Erikstein, R Kåresen, P E Lonning, E Skovlund, A L Børresen-Dale.   

Abstract

483 Norwegian breast cancer patients were screened for six different ataxia telangiectasia mutated (ATM) mutations previously found to account for 83% of the disease alleles in Norwegian ataxia telangiectasia (AT) patients. Only one carrier was found. These results provide no evidence in favour of an excess risk of breast cancer associated with heterozygosity for classical AT mutations, but remain consistent with a maximum 2.4-fold increased risk. Copyright 2000 Cancer Research Campaign.

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Year:  2000        PMID： 11104561      PMCID： PMC2363448          DOI： 10.1054/bjoc.2000.1519

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  25 in total

1.  Sequence analysis of the ATM gene in 20 patients with RTOG grade 3 or 4 acute and/or late tissue radiation side effects.

Authors:  U Oppitz; U Bernthaler; D Schindler; A Sobeck; H Hoehn; M Platzer; A Rosenthal; M Flentje
Journal:  Int J Radiat Oncol Biol Phys       Date:  1999-07-15       Impact factor: 7.038

2.  Heterozygous germline ATM mutations do not contribute to radiation-associated malignancies after Hodgkin's disease.

Authors:  K E Nichols; S Levitz; K E Shannon; D C Wahrer; D W Bell; G Chang; S Hegde; D Neuberg; T Shafman; N J Tarbell; P Mauch; C Ishioka; D A Haber; L Diller
Journal:  J Clin Oncol       Date:  1999-04       Impact factor: 44.544

3.  ATM-heterozygous germline mutations contribute to breast cancer-susceptibility.

Authors:  A Broeks; J H Urbanus; A N Floore; E C Dahler; J G Klijn; E J Rutgers; P Devilee; N S Russell; F E van Leeuwen; L J van 't Veer
Journal:  Am J Hum Genet       Date:  2000-02       Impact factor: 11.025

Review 4.  Cancer risk in ATM heterozygotes: a model of phenotypic and mechanistic differences between missense and truncating mutations.

Authors:  R A Gatti; A Tward; P Concannon
Journal:  Mol Genet Metab       Date:  1999-12       Impact factor: 4.797

5.  Identical mutation in 55% of the ATM alleles in 11 Norwegian AT families: evidence for a founder effect.

Authors:  K Laake; M Telatar; G A Geitvik; R O Hansen; A Heiberg; A M Andresen; R Gatti; A L Børresen-Dale
Journal:  Eur J Hum Genet       Date:  1998 May-Jun       Impact factor: 4.246

6.  Identification of germline missense mutations and rare allelic variants in the ATM gene in early-onset breast cancer.

Authors:  L Izatt; J Greenman; S Hodgson; D Ellis; S Watts; G Scott; C Jacobs; R Liebmann; M J Zvelebil; C Mathew; E Solomon
Journal:  Genes Chromosomes Cancer       Date:  1999-12       Impact factor: 5.006

7.  Breast cancer risk in ataxia telangiectasia (AT) heterozygotes: haplotype study in French AT families.

Authors:  N Janin; N Andrieu; K Ossian; A Laugé; M F Croquette; C Griscelli; M Debré; B Bressac-de-Paillerets; A Aurias; D Stoppa-Lyonnet
Journal:  Br J Cancer       Date:  1999-06       Impact factor: 7.640

8.  Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer.

Authors:  D G Bebb; Z Yu; J Chen; M Telatar; K Gelmon; N Phillips; R A Gatti; B W Glickman
Journal:  Br J Cancer       Date:  1999-08       Impact factor: 7.640

9.  Heterozygosity for mutations in the ataxia telangiectasia gene is not a major cause of radiotherapy complications in breast cancer patients.

Authors:  M Shayeghi; S Seal; J Regan; N Collins; R Barfoot; N Rahman; A Ashton; M Moohan; R Wooster; R Owen; J M Bliss; M R Stratton; J Yarnold
Journal:  Br J Cancer       Date:  1998-10       Impact factor: 7.640
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  1 in total

1.  ATM in breast and brain tumors: a comprehensive review.

Authors:  Mehrdad Asghari Estiar; Parvin Mehdipour
Journal:  Cancer Biol Med       Date:  2018-08       Impact factor: 4.248
  1 in total

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