Literature DB >> 10471049

Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer.

D G Bebb1, Z Yu, J Chen, M Telatar, K Gelmon, N Phillips, R A Gatti, B W Glickman.   

Abstract

Epidemiological evidence points to an increased risk of breast cancer in ataxia telangiectasia (AT) heterozygote women. Previous attempts to screen early onset or familial breast cancer patients failed to confirm an association. The issue of AT and late onset sporadic breast cancer remained unresolved. We screened 47 women who developed later onset, sporadic breast cancer for ataxia telangiectasia mutated (ATM) mutations. No mutations were found.

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Year:  1999        PMID： 10471049      PMCID： PMC2363154          DOI： 10.1038/sj.bjc.6690630

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  29 in total

1.  Ataxia-telangiectasia: mutations in ATM cDNA detected by protein-truncation screening.

Authors:  M Telatar; Z Wang; N Udar; T Liang; E Bernatowska-Matuszkiewicz; M Lavin; Y Shiloh; P Concannon; R A Good; R A Gatti
Journal:  Am J Hum Genet       Date:  1996-07       Impact factor: 11.025

2.  Mutations in BRCA1 and BRCA2 in breast cancer families: are there more breast cancer-susceptibility genes?

Authors:  O M Serova; S Mazoyer; N Puget; V Dubois; P Tonin; Y Y Shugart; D Goldgar; S A Narod; H T Lynch; G M Lenoir
Journal:  Am J Hum Genet       Date:  1997-03       Impact factor: 11.025

3.  Cancer-susceptibility genes. Gatekeepers and caretakers.

Authors:  K W Kinzler; B Vogelstein
Journal:  Nature       Date:  1997-04-24       Impact factor: 49.962

4.  Heterozygous ATM mutations do not contribute to early onset of breast cancer.

Authors:  M G FitzGerald; J M Bean; S R Hegde; H Unsal; D J MacDonald; D P Harkin; D M Finkelstein; K J Isselbacher; D A Haber
Journal:  Nat Genet       Date:  1997-03       Impact factor: 38.330

Review 5.  An update of HNPCC (Lynch syndrome).

Authors:  H T Lynch; T Smyrk; J Lynch
Journal:  Cancer Genet Cytogenet       Date:  1997-01

6.  Ataxia-telangiectasia: identification and detection of founder-effect mutations in the ATM gene in ethnic populations.

Authors:  M Telatar; S Teraoka; Z Wang; H H Chun; T Liang; S Castellvi-Bel; N Udar; A L Borresen-Dale; L Chessa; E Bernatowska-Matuszkiewicz; O Porras; M Watanabe; A Junker; P Concannon; R A Gatti
Journal:  Am J Hum Genet       Date:  1998-01       Impact factor: 11.025

7.  Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia.

Authors:  I Vorechovský; L Luo; M J Dyer; D Catovsky; P L Amlot; J C Yaxley; L Foroni; L Hammarström; A D Webster; M A Yuille
Journal:  Nat Genet       Date:  1997-09       Impact factor: 38.330

8.  Association of BRCA1 with Rad51 in mitotic and meiotic cells.

Authors:  R Scully; J Chen; A Plug; Y Xiao; D Weaver; J Feunteun; T Ashley; D M Livingston
Journal:  Cell       Date:  1997-01-24       Impact factor: 41.582

9.  Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2.

Authors:  S K Sharan; M Morimatsu; U Albrecht; D S Lim; E Regel; C Dinh; A Sands; G Eichele; P Hasty; A Bradley
Journal:  Nature       Date:  1997-04-24       Impact factor: 49.962

10.  Predominance of null mutations in ataxia-telangiectasia.

Authors:  S Gilad; R Khosravi; D Shkedy; T Uziel; Y Ziv; K Savitsky; G Rotman; S Smith; L Chessa; T J Jorgensen; R Harnik; M Frydman; O Sanal; S Portnoi; Z Goldwicz; N G Jaspers; R A Gatti; G Lenoir; M F Lavin; K Tatsumi; R D Wegner; Y Shiloh; A Bar-Shira
Journal:  Hum Mol Genet       Date:  1996-04       Impact factor: 6.150
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  9 in total

1.  Global analysis of ATM polymorphism reveals significant functional constraint.

Authors:  Y R Thorstenson; P Shen; V G Tusher; T L Wayne; R W Davis; G Chu; P J Oefner
Journal:  Am J Hum Genet       Date:  2001-07-03       Impact factor: 11.025

Review 2.  Genes other than BRCA1 and BRCA2 involved in breast cancer susceptibility.

Authors:  M M de Jong; I M Nolte; G J te Meerman; W T A van der Graaf; J C Oosterwijk; J H Kleibeuker; M Schaapveld; E G E de Vries
Journal:  J Med Genet       Date:  2002-04       Impact factor: 6.318

3.  Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer.

Authors:  Shaun P Scott; Regina Bendix; Philip Chen; Raymond Clark; Thilo Dork; Martin F Lavin
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-22       Impact factor: 11.205

4.  The Breast Cancer Tumor Suppressor TRIM29 Is Expressed via ATM-dependent Signaling in Response to Hypoxia.

Authors:  Muzaffer Dükel; W Scott Streitfeld; Tsz Ching Chloe Tang; Lindsey R F Backman; Lingbao Ai; W Stratford May; Kevin D Brown
Journal:  J Biol Chem       Date:  2016-08-17       Impact factor: 5.157

5.  Rapid flow cytometry-based structural maintenance of chromosomes 1 (SMC1) phosphorylation assay for identification of ataxia-telangiectasia homozygotes and heterozygotes.

Authors:  Shareef A Nahas; Anthony W Butch; Liutao Du; Richard A Gatti
Journal:  Clin Chem       Date:  2009-01-15       Impact factor: 8.327

6.  Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer.

Authors:  Sean V Tavtigian; Peter J Oefner; Davit Babikyan; Anne Hartmann; Sue Healey; Florence Le Calvez-Kelm; Fabienne Lesueur; Graham B Byrnes; Shu-Chun Chuang; Nathalie Forey; Corinna Feuchtinger; Lydie Gioia; Janet Hall; Mia Hashibe; Barbara Herte; Sandrine McKay-Chopin; Alun Thomas; Maxime P Vallée; Catherine Voegele; Penelope M Webb; David C Whiteman; Suleeporn Sangrajrang; John L Hopper; Melissa C Southey; Irene L Andrulis; Esther M John; Georgia Chenevix-Trench
Journal:  Am J Hum Genet       Date:  2009-09-24       Impact factor: 11.025

7.  Single nucleotide polymorphism D1853N of the ATM gene may alter the risk for breast cancer.

Authors:  M Schrauder; S Frank; P L Strissel; M P Lux; M R Bani; C Rauh; C C Sieber; K Heusinger; A Hartmann; R Schulz-Wendtland; R Strick; M W Beckmann; Peter A Fasching
Journal:  J Cancer Res Clin Oncol       Date:  2008-02-09       Impact factor: 4.553

8.  Screening breast cancer patients for Norwegian ATM mutations.

Authors:  K Laake; P Vu; T I Andersen; B Erikstein; R Kåresen; P E Lonning; E Skovlund; A L Børresen-Dale
Journal:  Br J Cancer       Date:  2000-12       Impact factor: 7.640

9.  ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer.

Authors:  J L Bernstein; L Bernstein; W D Thompson; C F Lynch; K E Malone; S L Teitelbaum; J H Olsen; H Anton-Culver; J D Boice; B S Rosenstein; A-L Børresen-Dale; R A Gatti; P Concannon; R W Haile
Journal:  Br J Cancer       Date:  2003-10-20       Impact factor: 7.640
  9 in total

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