Literature DB >> 11099264

PASS: prediction of activity spectra for biologically active substances.

A Lagunin1, A Stepanchikova, D Filimonov, V Poroikov.   

Abstract

The concept of the biological activity spectrum was introduced to describe the properties of biologically active substances. The PASS (prediction of activity spectra for substances) software product, which predicts more than 300 pharmacological effects and biochemical mechanisms on the basis of the structural formula of a substance, may be efficiently used to find new targets (mechanisms) for some ligands and, conversely, to reveal new ligands for some biological targets. We have developed a WWW interface for the PASS software. A WWW server for the on-line prediction of the biological activity spectra of substances has been constructed.

Mesh：

Year:  2000        PMID： 11099264     DOI： 10.1093/bioinformatics/16.8.747

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


  99 in total

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