Literature DB >> 11096776

Acute Treatment of Spinal Cord Injury.

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Abstract

At the authors' institution, a multidisciplinary team of trauma physicians, neurosurgeons, and anesthesiologists evaluates patients with suspected spinal cord injury. Our initial goal after resuscitation and evaluation is to assure adequate tissue oxygenation through blood pressure support and oxygen supplementation. This supplementation helps ensure maximal oxygen delivery to the injured spinal cord. It is important that a detailed and standardized neurologic examination is performed and repeated often to detect neurologic decline. Immediately after a potential spinal cord injury is identified, methylprednisolone is administered (ideally during transport from the accident scene). Plain x-rays of the spine are the first films obtained. Once a fracture is identified, a computerized CT scan through the identified region is done. If the injury involves the cervical spine, and reduction is needed to correct a deformity, closed reduction with placement of a halo-fixation device is performed in the emergency room. We believe that reduction to normal spinal alignment should be accomplished within a few hours of the injury. Once initial immobilization efforts are complete, the patient gets an magnetic resonance image (MRI) of the affected region. Most spinal cord injury patients at our institution do not undergo emergency surgery. Urgent surgery is only performed in those with continued neurologic decline, and MRI findings of acute compression from lesions such as a ruptured disc or epidural hematoma.

Entities:  

Year:  2000        PMID: 11096776     DOI: 10.1007/s11940-000-0030-1

Source DB:  PubMed          Journal:  Curr Treat Options Neurol        ISSN: 1092-8480            Impact factor:   3.598


  13 in total

1.  Steroids and gunshot wounds to the spine.

Authors:  R F Heary; A R Vaccaro; J J Mesa; B E Northrup; T J Albert; R A Balderston; J M Cotler
Journal:  Neurosurgery       Date:  1997-09       Impact factor: 4.654

Review 2.  A crash course in spinal cord injury.

Authors:  D Yu
Journal:  Postgrad Med       Date:  1998-08       Impact factor: 3.840

3.  Effect of surgery on motor recovery following traumatic spinal cord injury.

Authors:  R L Waters; R H Adkins; J S Yakura; I Sie
Journal:  Spinal Cord       Date:  1996-04       Impact factor: 2.772

4.  Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study.

Authors:  M B Bracken; M J Shepard; T R Holford; L Leo-Summers; E F Aldrich; M Fazl; M Fehlings; D L Herr; P W Hitchon; L F Marshall; R P Nockels; V Pascale; P L Perot; J Piepmeier; V K Sonntag; F Wagner; J E Wilberger; H R Winn; W Young
Journal:  JAMA       Date:  1997-05-28       Impact factor: 56.272

5.  Recovery of motor function after spinal-cord injury--a randomized, placebo-controlled trial with GM-1 ganglioside.

Authors:  F H Geisler; F C Dorsey; W P Coleman
Journal:  N Engl J Med       Date:  1991-06-27       Impact factor: 91.245

6.  An evidence-based review of decompressive surgery in acute spinal cord injury: rationale, indications, and timing based on experimental and clinical studies.

Authors:  M G Fehlings; C H Tator
Journal:  J Neurosurg       Date:  1999-07       Impact factor: 5.115

7.  Neurologic outcome of early versus late surgery for cervical spinal cord injury.

Authors:  A R Vaccaro; R J Daugherty; T P Sheehan; S J Dante; J M Cotler; R A Balderston; G J Herbison; B E Northrup
Journal:  Spine (Phila Pa 1976)       Date:  1997-11-15       Impact factor: 3.468

8.  Induction of tirilazad clearance by phenytoin.

Authors:  J C Fleishaker; L K Pearson; G R Peters
Journal:  Biopharm Drug Dispos       Date:  1998-03       Impact factor: 1.627

9.  GM-1 ganglioside administration combined with physical therapy restores ambulation in humans with chronic spinal cord injury.

Authors:  J B Walker; M Harris
Journal:  Neurosci Lett       Date:  1993-10-29       Impact factor: 3.046

10.  The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats.

Authors:  S Constantini; W Young
Journal:  J Neurosurg       Date:  1994-01       Impact factor: 5.115

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  1 in total

1.  Evaluation of neurologic deficit without apparent cause: the importance of a multidisciplinary approach.

Authors:  Harvey E Smith; Ralph E Rynning; Chukwuka Okafor; James Zaslavsky; Joseph I Tracy; John Ratliff; James Harrop; Todd Albert; Alan Hilibrand; Gregory Anderson; Ashwini Sharan; Zoe Brown; Alexander R Vaccaro
Journal:  J Spinal Cord Med       Date:  2007       Impact factor: 1.985

  1 in total

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