Literature DB >> 11091007

The safety of a ginger extract in the rat.

M S Weidner1, K Sigwart.   

Abstract

In three different studies on rats, the effects of a patented standardised ginger extract, EV.EXT 33, on blood glucose, blood coagulation, blood pressure and heart rate were investigated. EV.EXT 33 had no significant effect on blood glucose levels at the doses used. It also had no significant effects on coagulation parameters or on Warfarin-induced changes in blood coagulation, indicating that it did not interact with Warfarin. EV.EXT 33 neither decreases systolic blood pressure nor increases heart rate in the rat. As also seen from the literature, ginger is thus pharmacologically safe regarding the investigated aspects.

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Year:  2000        PMID: 11091007     DOI: 10.1016/s0378-8741(00)00340-8

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN: 0378-8741            Impact factor:   4.360


  12 in total

1.  The Role of 6-Gingerol on Inhibiting Amyloid β Protein-Induced Apoptosis in PC12 Cells.

Authors:  Gao-feng Zeng; Shao-hui Zong; Zhi-yong Zhang; Song-wen Fu; Ke-ke Li; Ye Fang; Li Lu; De-Qiang Xiao
Journal:  Rejuvenation Res       Date:  2015-08-20       Impact factor: 4.663

2.  6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.

Authors:  Xiao-Dong Pei; Zhi-Long He; Hong-Liang Yao; Jun-Song Xiao; Lan Li; Jian-Zhong Gu; Pei-Zhao Shi; Jin-Hua Wang; Li-He Jiang
Journal:  Eur J Nutr       Date:  2021-01-08       Impact factor: 5.614

3.  Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.

Authors:  Xuemin Jiang; Kenneth M Williams; Winston S Liauw; Alaina J Ammit; Basil D Roufogalis; Colin C Duke; Richard O Day; Andrew J McLachlan
Journal:  Br J Clin Pharmacol       Date:  2005-04       Impact factor: 4.335

Review 4.  Elucidating the Beneficial Effects of Ginger (Zingiber officinale Roscoe) in Parkinson's Disease.

Authors:  Efthalia Angelopoulou; Yam Nath Paudel; Sokratis G Papageorgiou; Christina Piperi
Journal:  ACS Pharmacol Transl Sci       Date:  2022-09-07

5.  Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats.

Authors:  Megha Saraswat; Palla Suryanarayana; Paduru Yadagiri Reddy; Madhoosudan A Patil; Nagalla Balakrishna; Geereddy Bhanuprakash Reddy
Journal:  Mol Vis       Date:  2010-08-10       Impact factor: 2.367

6.  Toxicological evaluation of grains of paradise (Aframomum melegueta) [Roscoe] K. Schum.

Authors:  Nebojsa Ilic; Barbara M Schmidt; Alexander Poulev; Ilya Raskin
Journal:  J Ethnopharmacol       Date:  2009-10-31       Impact factor: 4.360

7.  A 35-day gavage safety assessment of ginger in rats.

Authors:  Xianglu Rong; Gang Peng; Takuya Suzuki; Qinglin Yang; Johji Yamahara; Yuhao Li
Journal:  Regul Toxicol Pharmacol       Date:  2009-03-18       Impact factor: 3.271

8.  The Effect of Ginger (Zingiber officinale) on Platelet Aggregation: A Systematic Literature Review.

Authors:  Wolfgang Marx; Daniel McKavanagh; Alexandra L McCarthy; Robert Bird; Karin Ried; Alexandre Chan; Liz Isenring
Journal:  PLoS One       Date:  2015-10-21       Impact factor: 3.240

9.  Preventive and Protective Properties of Zingiber officinale (Ginger) in Diabetes Mellitus, Diabetic Complications, and Associated Lipid and Other Metabolic Disorders: A Brief Review.

Authors:  Yiming Li; Van H Tran; Colin C Duke; Basil D Roufogalis
Journal:  Evid Based Complement Alternat Med       Date:  2012-11-22       Impact factor: 2.629

10.  Anti-oxidative and anti-inflammatory effects of ginger in health and physical activity: review of current evidence.

Authors:  Nafiseh Shokri Mashhadi; Reza Ghiasvand; Gholamreza Askari; Mitra Hariri; Leila Darvishi; Mohammad Reza Mofid
Journal:  Int J Prev Med       Date:  2013-04
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