Literature DB >> 11089985

The future of ageing.

L Hayflick1.   

Abstract

Advances in our knowledge of age-associated diseases have far outpaced advances in our understanding of the fundamental ageing processes that underlie the vulnerability to these pathologies. If we are to increase human life expectancy beyond the fifteen-year limit that would result if today's leading causes of death were resolved, more attention must be paid to basic research on ageing. Determination of longevity must be distinguished from ageing to take us from the common question of why we age to a more revealing question that is rarely posed: why do we live as long as we do? But if the ability to intervene in ageing ever becomes a reality, it will be rife with unintended and undesirable consequences.

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Year:  2000        PMID: 11089985     DOI: 10.1038/35041709

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  45 in total

1.  Reprogramming somatic cell differentiation and the Hayflick Limit: contrasting two modern molecular bioengineering aims and their impact on the future of mankind.

Authors:  E S Sills; T Takeuchi; Z Rosenwaks; G D Palermo
Journal:  J Assist Reprod Genet       Date:  2001-08       Impact factor: 3.412

2.  Age, growth and size interact with stress to determine life span and mortality.

Authors:  Deborah Ann Roach
Journal:  Exp Gerontol       Date:  2012-06-01       Impact factor: 4.032

Review 3.  How long should telomeres be?

Authors:  A Aviv; C B Harley
Journal:  Curr Hypertens Rep       Date:  2001-04       Impact factor: 5.369

4.  Life extension technologies: economic, psychological, and social considerations.

Authors:  Leigh Turner
Journal:  HEC Forum       Date:  2003-09

5.  Genetic, physiological, and lifestyle predictors of mortality in the general population.

Authors:  Stefan Walter; Johan Mackenbach; Zoltán Vokó; Stefan Lhachimi; M Arfan Ikram; André G Uitterlinden; Anne B Newman; Joanne M Murabito; Melissa E Garcia; Vilmundur Gudnason; Toshiko Tanaka; Gregory J Tranah; Henri Wallaschofski; Thomas Kocher; Lenore J Launer; Nora Franceschini; Maarten Schipper; Albert Hofman; Henning Tiemeier
Journal:  Am J Public Health       Date:  2012-02-16       Impact factor: 9.308

6.  Global aging, well-ordered science, and prospection.

Authors:  Colin Farrelly
Journal:  Rejuvenation Res       Date:  2010-10       Impact factor: 4.663

7.  The Longitudinal Study of Aging in Human Young Adults: Knowledge Gaps and Research Agenda.

Authors:  Terrie E Moffitt; Daniel W Belsky; Andrea Danese; Richie Poulton; Avshalom Caspi
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2016-10-07       Impact factor: 6.053

8.  Chromosomal changes in ageing.

Authors:  Predrag Erceg; Dragoslav P Milosevic; Nebojsa Despotovic; Mladen Davidovic
Journal:  J Genet       Date:  2007-12       Impact factor: 1.166

Review 9.  Living longer: age retardation and autonomy.

Authors:  Elisabeth Hildt
Journal:  Med Health Care Philos       Date:  2008-07-31

Review 10.  Aging and Lung Disease. Clinical Impact and Cellular and Molecular Pathways.

Authors:  Mauricio Rojas; Ana L Mora; Maria Kapetanaki; Nathaniel Weathington; Mark Gladwin; Oliver Eickelberg
Journal:  Ann Am Thorac Soc       Date:  2015-12
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