Literature DB >> 11086019

Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics.

N Usman1, L M Blatt.   

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Year:  2000        PMID: 11086019      PMCID: PMC381444          DOI: 10.1172/JCI11631

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


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  20 in total

1.  Viral hepatitis.

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Review 3.  Antisense oligonucleotide inhibitors for the treatment of cancer: 2. Toxicological properties of phosphorothioate oligodeoxynucleotides.

Authors:  S P Henry; D Monteith; A A Levin
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Review 4.  Hepatitis C: the clinical spectrum of disease.

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Review 5.  Vascular endothelial growth factor, a potent and selective angiogenic agent.

Authors:  K A Thomas
Journal:  J Biol Chem       Date:  1996-01-12       Impact factor: 5.157

6.  Synthesis, deprotection, analysis and purification of RNA and ribozymes.

Authors:  F Wincott; A DiRenzo; C Shaffer; S Grimm; D Tracz; C Workman; D Sweedler; C Gonzalez; S Scaringe; N Usman
Journal:  Nucleic Acids Res       Date:  1995-07-25       Impact factor: 16.971

7.  Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance.

Authors:  L Beigelman; J A McSwiggen; K G Draper; C Gonzalez; K Jensen; A M Karpeisky; A S Modak; J Matulic-Adamic; A B DiRenzo; P Haeberli
Journal:  J Biol Chem       Date:  1995-10-27       Impact factor: 5.157

8.  Poliovirus chimeras replicating under the translational control of genetic elements of hepatitis C virus reveal unusual properties of the internal ribosomal entry site of hepatitis C virus.

Authors:  H H Lu; E Wimmer
Journal:  Proc Natl Acad Sci U S A       Date:  1996-02-20       Impact factor: 11.205

9.  In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence.

Authors:  T R Cech; A J Zaug; P J Grabowski
Journal:  Cell       Date:  1981-12       Impact factor: 41.582

10.  Sequence analysis of the 5' noncoding region of hepatitis C virus.

Authors:  J Bukh; R H Purcell; R H Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-01       Impact factor: 11.205

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  20 in total

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Review 4.  Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies.

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Review 5.  Therapeutic regulation of gene expression in the inner ear using RNA interference.

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Review 7.  Inhibition of vascular endothelial growth factor in the treatment of solid tumors.

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Review 8.  Targeted therapy for malignant melanoma.

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Review 9.  In vivo imaging with oligonucleotides for diagnosis and drug development.

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10.  Internal 32P-labeling of L-deoxyoligonucleotides.

Authors:  Christian Frauendorf; Felix Hausch; Ingo Röhl; Andrea Lichte; Stefan Vonhoff; Sven Klussmann
Journal:  Nucleic Acids Res       Date:  2003-04-01       Impact factor: 16.971

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