Literature DB >> 11083652

Antiretroviral agents inhibit infection of human cells by porcine endogenous retroviruses.

S K Powell1, M E Gates, G Langford, M L Gu, C Lockey, Z Long, E Otto.   

Abstract

The efficacy of antiretroviral drugs against porcine endogenous retroviruses (PERV) that may be harbored in pig organs intended for transplantation was examined in human cells in vitro. The nucleoside analogs zidovudine and dideoxyinosine were found to effectively inhibit PERV replication.

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Year:  2000        PMID： 11083652      PMCID： PMC90217          DOI： 10.1128/AAC.44.12.3432-3433.2000

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine.

Authors:  Q Gao; Z X Gu; M A Parniak; X G Li; M A Wainberg
Journal:  J Virol       Date:  1992-01       Impact factor: 5.103

2.  Evaluation of reverse transcriptase and protease inhibitors in two-drug combinations against human immunodeficiency virus replication.

Authors:  C A Deminie; C M Bechtold; D Stock; M Alam; F Djang; A H Balch; T C Chou; M Prichard; R J Colonno; P F Lin
Journal:  Antimicrob Agents Chemother       Date:  1996-06       Impact factor: 5.191

3.  Infection of human cells by an endogenous retrovirus of pigs.

Authors:  C Patience; Y Takeuchi; R A Weiss
Journal:  Nat Med       Date:  1997-03       Impact factor: 53.440

Review 4.  Stavudine: a review of its pharmacodynamic and pharmacokinetic properties and clinical potential in HIV infection.

Authors:  A P Lea; D Faulds
Journal:  Drugs       Date:  1996-05       Impact factor: 9.546

5.  Efficacy of antiretroviral agents against murine replication-competent retrovirus infection in human cells.

Authors:  S K Powell; M Artlip; M Kaloss; S Brazinski; R Lyons; G J McGarrity; E Otto
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

6.  Type C retrovirus released from porcine primary peripheral blood mononuclear cells infects human cells.

Authors:  C A Wilson; S Wong; J Muller; C E Davidson; T M Rose; P Burd
Journal:  J Virol       Date:  1998-04       Impact factor: 5.103

7.  Porcine endogenous retrovirus (PERV) was not transmitted from transplanted porcine endothelial cells to baboons in vivo.

Authors:  U Martin; G Steinhoff; V Kiessig; M Chikobava; M Anssar; T Morschheuser; B Lapin; A Haverich
Journal:  Transpl Int       Date:  1998       Impact factor: 3.782

8.  Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine.

Authors:  Z Gu; Q Gao; X Li; M A Parniak; M A Wainberg
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

9.  Didanosine resistance in HIV-infected patients switched from zidovudine to didanosine monotherapy.

Authors:  M J Kozal; K Kroodsma; M A Winters; R W Shafer; B Efron; D A Katzenstein; T C Merigan
Journal:  Ann Intern Med       Date:  1994-08-15       Impact factor: 25.391

10.  Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2',3'-didehydro-2',3'-dideoxythymidine in cell culture.

Authors:  S F Lacey; B A Larder
Journal:  Antimicrob Agents Chemother       Date:  1994-06       Impact factor: 5.191
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  15 in total

1.  Characterization of endogenous retroviruses in pig cell cultures.

Authors:  M Ferrari; M N Losio; A Corradi; S Vittori; A Tosini
Journal:  Vet Res Commun       Date:  2003-09       Impact factor: 2.459

2.  Evaluation of endogenous pig retrovirus expression and of tumorigenicity in nude mice.

Authors:  M Ferrari; A Corradi; P G Petronini; A Tosini; A Toniolo; C Robotti; R Moratti
Journal:  Vet Res Commun       Date:  2004-08       Impact factor: 2.459

3.  Transcriptional regulation of porcine endogenous retroviruses released from porcine and infected human cells by heterotrimeric protein complex NF-Y and impact of immunosuppressive drugs.

Authors:  Gregor Scheef; Nicole Fischer; Egbert Flory; Isabel Schmitt; Ralf R Tönjes
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

4.  Restriction of porcine endogenous retrovirus by porcine APOBEC3 cytidine deaminases.

Authors:  Eva Dörrschuck; Nicole Fischer; Ignacio G Bravo; Kay-Martin Hanschmann; Heidi Kuiper; Andreas Spötter; Ronny Möller; Klaus Cichutek; Carsten Münk; Ralf R Tönjes
Journal:  J Virol       Date:  2011-02-09       Impact factor: 5.103

Review 5.  Infection barriers to successful xenotransplantation focusing on porcine endogenous retroviruses.

Authors:  Joachim Denner; Ralf R Tönjes
Journal:  Clin Microbiol Rev       Date:  2012-04       Impact factor: 26.132

6.  Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.

Authors:  Minyi Shi; Xin Wang; Erik De Clercq; Sonshin Takao; Masanori Baba
Journal:  Antimicrob Agents Chemother       Date:  2007-04-30       Impact factor: 5.191

7.  Molecular and enzymatic characterization of the porcine endogenous retrovirus protease.

Authors:  Jürgen H Blusch; Sigrid Seelmeir; Klaus von der Helm
Journal:  J Virol       Date:  2002-08       Impact factor: 5.103

8.  Susceptibility of porcine endogenous retrovirus to anti-retroviral inhibitors.

Authors:  Takele Argaw; Winston Colon-Moran; Carolyn Wilson
Journal:  Xenotransplantation       Date:  2016-03-29       Impact factor: 3.907

9.  Infection in xenotransplantation: opportunities and challenges.

Authors:  Jay A Fishman
Journal:  Curr Opin Organ Transplant       Date:  2019-10       Impact factor: 2.640

10.  Intracellularly expressed single-domain antibody against p15 matrix protein prevents the production of porcine retroviruses.

Authors:  Sylvia Dekker; Wendy Toussaint; George Panayotou; Ton de Wit; Pim Visser; Frank Grosveld; Dubravka Drabek
Journal:  J Virol       Date:  2003-11       Impact factor: 5.103
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