Literature DB >> 11083183

The utility of polysporin ointment in the eradication of methicillin-resistant Staphylococcus aureus colonization: a pilot study.

S Fung1, S O'Grady, C Kennedy, H Dedier, I Campbell, J Conly.   

Abstract

We evaluated the efficacy of an ointment containing bacitracin, polymyxin B, and gramicidin for the eradication of colonization by methicillin-resistant Staphylococcus aureus in 11 medical patients, 10 (91%) of whom had previously failed a 1-week course of topical mupirocin. Mupirocin resistance was documented in 5 (45%) of 11 patients. Successful decolonization was achieved in 9 (82%) of 11 patients (based on 2 months of follow-up).

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Year:  2000        PMID： 11083183     DOI： 10.1086/501709

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN： 0899-823X            Impact factor:   3.254


  11 in total

1.  A randomized controlled trial comparing mupirocin and polysporin triple ointments in peritoneal dialysis patients: the MP3 Study.

Authors:  Rory F McQuillan; Ernest Chiu; Sharon Nessim; Charmaine E Lok; Janet M Roscoe; Paul Tam; Sarbjit Vanita Jassal
Journal:  Clin J Am Soc Nephrol       Date:  2011-12-01       Impact factor: 8.237

2.  Lysostaphin cream eradicates Staphylococcus aureus nasal colonization in a cotton rat model.

Authors:  John F Kokai-Kun; Scott M Walsh; Tanya Chanturiya; James J Mond
Journal:  Antimicrob Agents Chemother       Date:  2003-05       Impact factor: 5.191

3.  Nasal colonization with methicillin-resistant Staphylococcus aureus: clinical implications and treatment.

Authors:  David Friedel; Michael Climo
Journal:  Curr Infect Dis Rep       Date:  2007-05       Impact factor: 3.725

4.  A double-blind, randomized, controlled trial of topical polysporin triple compound versus topical mupirocin for the eradication of colonization with methicillin-resistant Staphylococcus aureus in a complex continuing care population.

Authors:  S O'Grady; Z Hirji; B Pejcic-Karapetrovic; S Fung; H Dedier; J Takata-Shewchuk; K Zhang; J Conly
Journal:  Can J Infect Dis Med Microbiol       Date:  2009       Impact factor: 2.471

5.  Nasal Carriage of Staphylococcus aureus As a Risk Factor for Skin and Soft Tissue Infections.

Authors:  J. John Weems; Luna B. Beck
Journal:  Curr Infect Dis Rep       Date:  2002-10       Impact factor: 3.725

6.  Combined topical and oral antimicrobial therapy for the eradication of methicillin-resistant Staphylococcus aureus (MRSA) colonization in hospitalized patients.

Authors:  Scott K Fung; Marie Louie; Andrew E Simor
Journal:  Can J Infect Dis       Date:  2002-09

7.  Membrane damage elicits an immunomodulatory program in Staphylococcus aureus.

Authors:  Ahmed S Attia; Meredith A Benson; Devin L Stauff; Victor J Torres; Eric P Skaar
Journal:  PLoS Pathog       Date:  2010-03-12       Impact factor: 6.823

8.  Direct detection of Staphylococcus aureus from adult and neonate nasal swab specimens using real-time polymerase chain reaction.

Authors:  Suzanne M Paule; Anna C Pasquariello; Donna M Hacek; Adrienne G Fisher; Richard B Thomson; Karen L Kaul; Lance R Peterson
Journal:  J Mol Diagn       Date:  2004-08       Impact factor: 5.568

Review 9.  Decolonization in Prevention of Health Care-Associated Infections.

Authors:  Edward J Septimus; Marin L Schweizer
Journal:  Clin Microbiol Rev       Date:  2016-04       Impact factor: 26.132

10.  Staphylococcus aureus resistance to topical antimicrobials in atopic dermatitis.

Authors:  Giancarlo Rezende Bessa; Vanessa Petry Quinto; Daiane Corrêa Machado; Caroline Lipnharski; Magda Blessmann Weber; Renan Rangel Bonamigo; Pedro Alves D'Azevedo
Journal:  An Bras Dermatol       Date:  2016 Sep-Oct       Impact factor: 1.896
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