BACKGROUND: In many cases, incisional hernia repair requires the use of prosthetic materials. The aim of this experimental study in a rat model was to assess the role of polyglactin 910 mesh and fluoropassivated polyester mesh in preventing the formation of adhesions. METHODS: In the first experiment, the formation of peritoneal adhesions was assessed after insertion of polypropylene, polypropylene combined with polyglactin 910, or no mesh. In the second experiment, adhesion formations were compared after insertion of fluoropassivated polyester, polypropylene, and no mesh. RESULTS: The first experiment showed no significant difference in adhesion formations between the polypropylene mesh and the combined mesh; however, when no mesh was used, there were significantly fewer adhesions in both experiments (p < 0.01). The second experiment showed a significantly lower degree of adhesions and a lower Adhesion Index after insertion of fluoropassivated polyester mesh than when polypropylene mesh was used (p = 0.04). CONCLUSIONS: Adding polyglactin 910 mesh to polypropylene mesh to prevent the formation of adhesions is not an effective measure. Fluoropassivated polyester meshes appear to provide a better alternative to the use of polypropylene meshes for incisional hernia repair in humans in terms of the formation of adhesions.
BACKGROUND: In many cases, incisional hernia repair requires the use of prosthetic materials. The aim of this experimental study in a rat model was to assess the role of polyglactin 910 mesh and fluoropassivated polyester mesh in preventing the formation of adhesions. METHODS: In the first experiment, the formation of peritoneal adhesions was assessed after insertion of polypropylene, polypropylene combined with polyglactin 910, or no mesh. In the second experiment, adhesion formations were compared after insertion of fluoropassivated polyester, polypropylene, and no mesh. RESULTS: The first experiment showed no significant difference in adhesion formations between the polypropylene mesh and the combined mesh; however, when no mesh was used, there were significantly fewer adhesions in both experiments (p < 0.01). The second experiment showed a significantly lower degree of adhesions and a lower Adhesion Index after insertion of fluoropassivated polyester mesh than when polypropylene mesh was used (p = 0.04). CONCLUSIONS: Adding polyglactin 910 mesh to polypropylene mesh to prevent the formation of adhesions is not an effective measure. Fluoropassivated polyester meshes appear to provide a better alternative to the use of polypropylene meshes for incisional hernia repair in humans in terms of the formation of adhesions.
Authors: M Kiudelis; J Jonciauskiene; O Deduchovas; A Radziunas; A Mickevicius; D Janciauskas; S Petrovas; Z Endzinas; J Pundzius Journal: Hernia Date: 2006-09-15 Impact factor: 4.739
Authors: Juan Antonio Martín-Cartes; Salvador Morales-Conde; Juan Manuel Suárez-Grau; Manuel Bustos-Jiménez; Jean-Marie Hisnard Cadet-Dussort; Francisco López-Bernal; Juan Morcillo-Azcárate; Juan David Tutosaus-Gómez; Salvador Morales-Méndez Journal: Surg Today Date: 2008-02-01 Impact factor: 2.549
Authors: Markus Winny; Lavinia Maegel; Leonie Victoria Grethe; Danny Jonigk; Paul Borchert; Alexander Kaltenborn; Harald Schrem; Juergen Klempnauer; Daniel Poehnert Journal: Am J Transl Res Date: 2016-12-15 Impact factor: 4.060
Authors: Juan Martín-Cartes; Salvador Morales-Conde; Juan Suárez-Grau; Francisco López-Bernal; Manuel Bustos-Jiménez; Hisnard Cadet-Dussort; María Socas-Macías; José Alamo-Martínez; Juan D Tutosaus-Gómez; Slavador Morales-Mendez Journal: Surg Endosc Date: 2008-03 Impact factor: 4.584