Literature DB >> 11076554

Three new scalarane sesterterpenoids from the Okinawan sponge Hyrtios erectus.

H Miyaoka1, S Nishijima, H Mitome, Y Yamada.   

Abstract

Three new scalarane sesterterpenoids-hyrtiolide (1), 16-hydroxyscalarolide (2), and 12-deacetyl-Delta(17)-hyrtial (3), were isolated from Okinawan sponge Hyrtios erectus, along with scalarolide (4) and 12-deacetylhyrtial (5). The structures of new compounds 1-3 were determined by spectroscopic analysis and chemical conversions. Compounds 3 and 5 showed antiproliferative activity toward KB cells.

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Year:  2000        PMID： 11076554     DOI： 10.1021/np000115g

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  7 in total

1.  Antineoplastic agents. 542. Isolation and structure of sesterstatin 6 from the Indian Ocean sponge Hyrtios erecta.

Authors:  George R Pettit; Rui Tan; Zbigniew A Cichacz
Journal:  J Nat Prod       Date:  2005-08       Impact factor: 4.050

2.  Antiproliferative Scalarane-Based Metabolites from the Red Sea Sponge Hyrtios erectus.

Authors:  Sameh S Elhady; Ahmed M Al-Abd; Ali M El-Halawany; Abdulrahman M Alahdal; Hashim A Hassanean; Safwat A Ahmed
Journal:  Mar Drugs       Date:  2016-07-08       Impact factor: 5.118

Review 3.  Bioactive Natural Products of Marine Sponges from the Genus Hyrtios.

Authors:  Nourhan Hisham Shady; Ebaa M El-Hossary; Mostafa A Fouad; Tobias A M Gulder; Mohamed Salah Kamel; Usama Ramadan Abdelmohsen
Journal:  Molecules       Date:  2017-05-11       Impact factor: 4.411

4.  Scalalactams A⁻D, Scalarane Sesterterpenes with a γ-Lactam Moiety from a Korean Spongia Sp. Marine Sponge.

Authors:  Inho Yang; Jusung Lee; Jihye Lee; Dongyup Hahn; Jungwook Chin; Dong Hwan Won; Jaeyoung Ko; Hyukjae Choi; Ahreum Hong; Sang-Jip Nam; Heonjoong Kang
Journal:  Molecules       Date:  2018-12-03       Impact factor: 4.411

5.  Bioactive compounds from the Red Sea marine sponge Hyrtios species.

Authors:  Diaa T A Youssef; Lamiaa A Shaala; Hani Z Asfour
Journal:  Mar Drugs       Date:  2013-03-28       Impact factor: 5.118

6.  Anti-Helicobacter, Antitubercular and Cytotoxic Activities of Scalaranes from the Red Sea Sponge Hyrtios erectus.

Authors:  Abdulrahman M Alahdal; Hani Z Asfour; Safwat A Ahmed; Ahmad O Noor; Ahmed M Al-Abd; Mahmoud A Elfaky; Sameh S Elhady
Journal:  Molecules       Date:  2018-04-23       Impact factor: 4.411

7.  Cytotoxic Scalarane Sesterterpenes from the Sponge Hyrtios erectus.

Authors:  Oh-Seok Kwon; Donghwa Kim; Chang-Kwon Kim; Jeongyoon Sun; Chung J Sim; Dong-Chan Oh; Sang Koo Lee; Ki-Bong Oh; Jongheon Shin
Journal:  Mar Drugs       Date:  2020-05-13       Impact factor: 5.118
  7 in total

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