Literature DB >> 11074343

Celloidin mounting (embedding without infiltration) - a new, simple and reliable method for producing serial sections of high thickness through complete human brains and its application to stereological and immunohistochemical investigations.

H Heinsen1, T Arzberger, C Schmitz.   

Abstract

Celloidin mounting (embedding without infiltration) of the human central nervous system (CNS) proved to be superior to gelatin embedding for the production of serial sections ranging in thickness from 220 to 500 microm. After gallocyanin-staining, a comprehensive neuroanatomical as well as neuropathological survey of the human brain is possible, including diagnosis of Alzheimer's disease. Details of a fractionator analysis of the total striatal neuron number are described and the possible quantitative analysis of parallel immunohistochemically stained sections is discussed.

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Year:  2000        PMID： 11074343     DOI： 10.1016/s0891-0618(00)00067-3

Source DB:  PubMed          Journal:  J Chem Neuroanat        ISSN： 0891-0618            Impact factor:   3.052


  32 in total

1.  Enrichment of single neurons and defined brain regions from human brain tissue samples for subsequent proteome analysis.

Authors:  Mariana Molina; Simone Steinbach; Young Mok Park; Su Yeong Yun; Ana Tereza Di Lorenzo Alho; Helmut Heinsen; Lea T Grinberg; Katrin Marcus; Renata E Paraizo Leite; Caroline May
Journal:  J Neural Transm (Vienna)       Date:  2015-06-30       Impact factor: 3.575

2.  Subregional basal forebrain atrophy in Alzheimer's disease: a multicenter study.

Authors:  Ingo Kilimann; Michel Grothe; Helmut Heinsen; Eduardo Joaquim Lopez Alho; Lea Grinberg; Edson Amaro; Gláucia Aparecida Bento Dos Santos; Rafael Emídio da Silva; Alex J Mitchell; Giovanni B Frisoni; Arun L W Bokde; Andreas Fellgiebel; Massimo Filippi; Harald Hampel; Stefan Klöppel; Stefan J Teipel
Journal:  J Alzheimers Dis       Date:  2014       Impact factor: 4.472

3.  A novel approach for integrative studies on neurodegenerative diseases in human brains.

Authors:  Panos Theofilas; Livia Polichiso; Xuehua Wang; Luzia C Lima; Ana T L Alho; Renata E P Leite; Claudia K Suemoto; Carlos A Pasqualucci; Wilson Jacob-Filho; Helmut Heinsen; Lea T Grinberg
Journal:  J Neurosci Methods       Date:  2014-02-03       Impact factor: 2.390

4.  Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans.

Authors:  Panos Theofilas; Alexander J Ehrenberg; Austin Nguy; Julia M Thackrey; Sara Dunlop; Maria B Mejia; Ana T Alho; Renata Elaine Paraizo Leite; Roberta Diehl Rodriguez; Claudia K Suemoto; Camila F Nascimento; Marcus Chin; Daniel Medina-Cleghorn; Ana Maria Cuervo; Michelle Arkin; William W Seeley; Bruce L Miller; Ricardo Nitrini; Carlos Augusto Pasqualucci; Wilson Jacob Filho; Udo Rueb; John Neuhaus; Helmut Heinsen; Lea T Grinberg
Journal:  Neurobiol Aging       Date:  2017-09-20       Impact factor: 4.673

5.  Magnetic resonance diffusion tensor imaging for the pedunculopontine nucleus: proof of concept and histological correlation.

Authors:  A T D L Alho; C Hamani; E J L Alho; R E da Silva; G A B Santos; R C Neves; L L Carreira; C M M Araújo; G Magalhães; D B Coelho; M C Alegro; M G M Martin; L T Grinberg; C A Pasqualucci; H Heinsen; E T Fonoff; E Amaro
Journal:  Brain Struct Funct       Date:  2017-03-10       Impact factor: 3.270

6.  Immunohistochemical markers for quantitative studies of neurons and glia in human neocortex.

Authors:  Lise Lyck; Ishar Dalmau; John Chemnitz; Bente Finsen; Henrik Daa Schrøder
Journal:  J Histochem Cytochem       Date:  2007-11-12       Impact factor: 2.479

7.  Three-dimensional and stereological characterization of the human substantia nigra during aging.

Authors:  Ana Tereza Di Lorenzo Alho; Claudia Kimie Suemoto; Lívia Polichiso; Edilaine Tampellini; Kátia Cristina de Oliveira; Mariana Molina; Glaucia Aparecida Bento Santos; Camila Nascimento; Renata Elaine Paraizo Leite; Renata Eloah de Lucena Ferreti-Rebustini; Alexandre Valotta da Silva; Ricardo Nitrini; Carlos Augusto Pasqualucci; Wilson Jacob-Filho; Helmut Heinsen; Lea Tenenholz Grinberg
Journal:  Brain Struct Funct       Date:  2015-09-19       Impact factor: 3.270

8.  Pathoarchitectonics of the cerebral cortex in chorea-acanthocytosis and Huntington's disease.

Authors:  J Liu; H Heinsen; L T Grinberg; E Alho; E Amaro; C A Pasqualucci; U Rüb; K Seidel; W den Dunnen; T Arzberger; C Schmitz; M C Kiessling; B Bader; A Danek
Journal:  Neuropathol Appl Neurobiol       Date:  2018-06-10       Impact factor: 8.090

9.  Brain atrophy in primary progressive aphasia involves the cholinergic basal forebrain and Ayala's nucleus.

Authors:  Stefan J Teipel; Wilhelm Flatz; Nibal Ackl; Michel Grothe; Ingo Kilimann; Arun L W Bokde; Lea Grinberg; Edson Amaro; Vanja Kljajevic; Eduardo Alho; Christina Knels; Anne Ebert; Helmut Heinsen; Adrian Danek
Journal:  Psychiatry Res       Date:  2013-12-06       Impact factor: 3.222

10.  The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes.

Authors:  Jerzy Wegiel; Izabela Kuchna; Krzysztof Nowicki; Humi Imaki; Jarek Wegiel; Elaine Marchi; Shuang Yong Ma; Abha Chauhan; Ved Chauhan; Teresa Wierzba Bobrowicz; Mony de Leon; Leslie A Saint Louis; Ira L Cohen; Eric London; W Ted Brown; Thomas Wisniewski
Journal:  Acta Neuropathol       Date:  2010-03-03       Impact factor: 17.088
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