Literature DB >> 1107228

Cephamycins: a review, prospects and some original observations.

J M Hamilton-Miller, W Brumfitt.   

Abstract

The cephamycins are a group with great potential. The first member of the group intended for therapeutic use offers the following advantages over existing cephalosporins: 1. Stability to various beta-lactamases; in an environment increasingly threatened by R-factors, this property may be of increasing value as time passes. 2. Possible lack of cross-allergenicity with other beta-lactam antibiotics. 3. Activity against anaerobic strains. Cefoxitin is only the first semi-synthetic derivative; presumably there are other compounds awaiting assessment which have even more favourable properties.

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Year:  1975        PMID： 1107228     DOI： 10.1007/bf01642764

Source DB:  PubMed          Journal:  Infection        ISSN： 0300-8126            Impact factor:   3.553


  29 in total

1.  An in vivo comparison of cefoxitin, a semi-synthetic cephamycin, with cephalothin.

Authors:  J M Hamilton-Miller; D W Kerry; W Brumfitt
Journal:  J Antibiot (Tokyo)       Date:  1974-01       Impact factor: 2.649

2.  Phlebitis associated with cephalosporins: cephapirin versus cephalothin.

Authors:  J Inagaki; G P Bodey
Journal:  Curr Ther Res Clin Exp       Date:  1973-02

3.  Semisynthetic cephalosporins via a novel acyl exchange reaction.

Authors:  S Karady; S H Pines; L M Weinstock; F E Roberts; G S Brenner; A M Hoinowski; T Y Cheng; M Sletzinger
Journal:  J Am Chem Soc       Date:  1972-02-23       Impact factor: 15.419

4.  Substituted penicillin and cephalosporin derivatives. I. Stereospecific introduction of the C-6(7) methoxy group.

Authors:  L D Cama; W J Leanza; T R Beattie; B G Christensen
Journal:  J Am Chem Soc       Date:  1972-02-23       Impact factor: 15.419

5.  Beta-lactam antibiotics from Streptomyces.

Authors:  R Nagarajan; L D Boeck; M Gorman; R L Hamill; C E Higgens; M M Hoehn; W M Stark; J G Whitney
Journal:  J Am Chem Soc       Date:  1971-05-05       Impact factor: 15.419

6.  Cephamycins, a new family of beta-lactam antibiotics. IV. In vivo studies.

Authors:  A K Miller; E Celozzi; Y Kong; B A Pelak; H Kropp; E O Stapley; D Hendlin
Journal:  Antimicrob Agents Chemother       Date:  1972-10       Impact factor: 5.191

7.  Cephamycins, a new family of beta-lactam antibiotics. 3. In vitro studies.

Authors:  A K Miller; E Celozzi; B A Pelak; E O Stapley; D Hendlin
Journal:  Antimicrob Agents Chemother       Date:  1972-10       Impact factor: 5.191

8.  Cefoxitin, a semisynthetic cephamycin antibiotic: susceptibility studies.

Authors:  H Wallick; D Hendlin
Journal:  Antimicrob Agents Chemother       Date:  1974-01       Impact factor: 5.191

9.  Specificities of haemagglutinating antibodies evoked by members of the cephalosporin C family and benzylpenicillin.

Authors:  J M Hamilton-Miller; E P Abraham
Journal:  Biochem J       Date:  1971-06       Impact factor: 3.857

10.  Cephamycins, a new family of beta-lactam antibiotics. I. Production by actinomycetes, including Streptomyces lactamdurans sp. n.

Authors:  E O Stapley; M Jackson; S Hernandez; S B Zimmerman; S A Currie; S Mochales; J M Mata; H B Woodruff; D Hendlin
Journal:  Antimicrob Agents Chemother       Date:  1972-09       Impact factor: 5.191
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  1 in total

1.  Cefoxitin: a hospital study.

Authors:  A M Geddes; L P Schnurr; A P Ball; D McGhie; G R Brookes; R Wise; J Andrews
Journal:  Br Med J       Date:  1977-04-30
  1 in total

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