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Literature DB >> 11067860

LRP in Alzheimer's disease: friend or foe?

P G Ulery¹, D K Strickland.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2000 PMID： 11067860 PMCID： PMC301424 DOI： 10.1172/JCI11455

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

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24 in total

Review 1. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans.

Authors: M S Brown; J Ye; R B Rawson; J L Goldstein
Journal: Cell Date: 2000-02-18 Impact factor: 41.582

2. Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide.

Authors: S M Hammad; S Ranganathan; E Loukinova; W O Twal; W S Argraves
Journal: J Biol Chem Date: 1997-07-25 Impact factor: 5.157

3. Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.

Authors: P G Ulery; J Beers; I Mikhailenko; R E Tanzi; G W Rebeck; B T Hyman; D K Strickland
Journal: J Biol Chem Date: 2000-03-10 Impact factor: 5.157

4. Alpha2-macroglobulin enhances the clearance of endogenous soluble beta-amyloid peptide via low-density lipoprotein receptor-related protein in cortical neurons.

Authors: Z Qiu; D K Strickland; B T Hyman; G W Rebeck
Journal: J Neurochem Date: 1999-10 Impact factor: 5.372

5. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.

Authors: R Vassar; B D Bennett; S Babu-Khan; S Kahn; E A Mendiaz; P Denis; D B Teplow; S Ross; P Amarante; R Loeloff; Y Luo; S Fisher; J Fuller; S Edenson; J Lile; M A Jarosinski; A L Biere; E Curran; T Burgess; J C Louis; F Collins; J Treanor; G Rogers; M Citron
Journal: Science Date: 1999-10-22 Impact factor: 47.728

6. Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner.

Authors: D S Yang; D H Small; U Seydel; J D Smith; J Hallmayer; S E Gandy; R N Martins
Journal: Neuroscience Date: 1999 Impact factor: 3.590

7. Aberrant presenilin-1 expression downregulates LDL receptor-related protein (LRP): is LRP central to Alzheimer's disease pathogenesis?

Authors: E Van Uden; G Carlson; P St George-Hyslop; D Westaway; R Orlando; M Mallory; E Rockenstein; E Masliah
Journal: Mol Cell Neurosci Date: 1999-08 Impact factor: 4.314

8. Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1.

Authors: Y M Li; M Xu; M T Lai; Q Huang; J L Castro; J DiMuzio-Mower; T Harrison; C Lellis; A Nadin; J G Neduvelil; R B Register; M K Sardana; M S Shearman; A L Smith; X P Shi; K C Yin; J A Shafer; S J Gardell
Journal: Nature Date: 2000-06-08 Impact factor: 49.962

9. Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation.

Authors: W Q Qiu; D M Walsh; Z Ye; K Vekrellis; J Zhang; M B Podlisny; M R Rosner; A Safavi; L B Hersh; D J Selkoe
Journal: J Biol Chem Date: 1998-12-04 Impact factor: 5.157

10. Alpha-2 macroglobulin is genetically associated with Alzheimer disease.

Authors: D Blacker; M A Wilcox; N M Laird; L Rodes; S M Horvath; R C Go; R Perry; B Watson; S S Bassett; M G McInnis; M S Albert; B T Hyman; R E Tanzi
Journal: Nat Genet Date: 1998-08 Impact factor: 38.330

9 in total

Review 1. Multi-dimensional mass spectrometry-based shotgun lipidomics and the altered lipids at the mild cognitive impairment stage of Alzheimer's disease.

Authors: Xianlin Han
Journal: Biochim Biophys Acta Date: 2010-02-01

2. Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues.

Authors: Ashani T Weeraratna; Audrey Kalehua; Isoke Deleon; Dorothy Bertak; Gregory Maher; Michael S Wade; Ana Lustig; Kevin G Becker; William Wood; Douglas G Walker; Thomas G Beach; Dennis D Taub
Journal: Exp Cell Res Date: 2006-11-01 Impact factor: 3.905

3. Partial Endothelial Nitric Oxide Synthase Deficiency Exacerbates Cognitive Deficit and Amyloid Pathology in the APPswe/PS1ΔE9 Mouse Model of Alzheimer's Disease.

Authors: Sara Ahmed; Yu Jing; Bruce G Mockett; Hu Zhang; Wickliffe C Abraham; Ping Liu
Journal: Int J Mol Sci Date: 2022-06-30 Impact factor: 6.208

Review 4. Potential mechanisms contributing to sulfatide depletion at the earliest clinically recognizable stage of Alzheimer's disease: a tale of shotgun lipidomics.

Authors: Xianlin Han
Journal: J Neurochem Date: 2007-11 Impact factor: 5.372