| Literature DB >> 11062496 |
E Meffre1, R Casellas, M C Nussenzweig.
Abstract
Antibodies on the surface of B lymphocytes trigger adaptive immune responses and control a series of antigen-independent checkpoints during B cell development. These physiologic processes are regulated by a complex of membrane immunoglobulin and two signal transducing proteins known as Ig alpha and Ig beta. Here we focus on the role of antibodies in governing the maturation of B cells from early antigen-independent through the final antigen-dependent stages.Entities:
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Year: 2000 PMID: 11062496 DOI: 10.1038/80816
Source DB: PubMed Journal: Nat Immunol ISSN: 1529-2908 Impact factor: 25.606