Literature DB >> 1105696

The effect of indomethacin on plasma renin activity in man under normal conditions and after stimulation of the renin angiotensin system.

K W Rumpf, S Frenzel, H D Lowitz, F Scheler.   

Abstract

1) The influence of oral indomethacin on basal and stimulated plasma renin activity in normal human subjects was determined. 2) Indomethacin lowers the basal plasma renin activity in man. 3) The response of the plasma renin activity after indomethacin to physiological and pharmacological stimuli is maintained at a lower level. 4) There is no evidence from our experiments that major changes in the sodium balance are responsible for the effects observed.

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Year:  1975        PMID: 1105696     DOI: 10.1016/s0090-6980(75)80011-6

Source DB:  PubMed          Journal:  Prostaglandins        ISSN: 0090-6980


  11 in total

1.  Effect of indapamide on the renin-aldosterone system, and urinary excretion of potassium and calcium in essential hypertension.

Authors:  H Danielsen; E B Pedersen; E S Spencer
Journal:  Br J Clin Pharmacol       Date:  1984-08       Impact factor: 4.335

2.  [Role of prostaglandins in the regulation of renin (author's transl)].

Authors:  J C Frölich
Journal:  Klin Wochenschr       Date:  1981-10-15

Review 3.  The involvement of arachidonic acid metabolism in the control of renin release.

Authors:  C Patrono; F Pugliese
Journal:  J Endocrinol Invest       Date:  1980 Apr-Jun       Impact factor: 4.256

4.  Role of renal prostaglandins in sympathetically mediated renin relase in the rat.

Authors:  W B Campbell; R M Graham; E K Jackson
Journal:  J Clin Invest       Date:  1979-08       Impact factor: 14.808

5.  [Plasma angiotensin-I-converting-enzyme activity after inhibition of prostaglandin synthesis (author's transl)].

Authors:  K W Rumpf; R Vetter; F Wendelken; F Scheler
Journal:  Klin Wochenschr       Date:  1980-05-02

Review 6.  Prostaglandins, thromboxanes and leukotrienes in clinical medicine.

Authors:  R D Zipser; G Laffi
Journal:  West J Med       Date:  1985-10

7.  The effects of ibuprofen and indomethacin on renal function in the presence and absence of frusemide in healthy volunteers on a restricted sodium diet.

Authors:  A P Passmore; S Copeland; G D Johnston
Journal:  Br J Clin Pharmacol       Date:  1990-03       Impact factor: 4.335

Review 8.  Effects of non-narcotic analgesics on the kidney.

Authors:  P Kincaid-Smith
Journal:  Drugs       Date:  1986       Impact factor: 9.546

9.  Furosemide fails to alter plasma active or inactive renin in conscious sheep but does so in anaesthetized animals.

Authors:  D J Lush; K A Munday; A R Noble
Journal:  J Physiol       Date:  1983-07       Impact factor: 5.182

10.  The effect of carbidopa and indomethacin on the renal response to gamma-L-glutamyl-L-dopa in normal man.

Authors:  R F Jeffrey; T M MacDonald; K Marwick; M R Lee
Journal:  Br J Clin Pharmacol       Date:  1988-02       Impact factor: 4.335

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