Literature DB >> 11050427

BRCA1: exploring the links to transcription.

A N Monteiro1.   

Abstract

Progress on determining the function of the breast and ovarian cancer susceptibility gene BRCA1 suggests it might be involved in two fundamental cellular processes: DNA repair and transcriptional regulation. Recent developments indicate that BRCA1 is a multifunctional protein, and disruption of its transcriptional activity could be crucial for tumor development.

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Year:  2000        PMID: 11050427     DOI: 10.1016/s0968-0004(00)01632-7

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  32 in total

1.  BRCA1 can stimulate gene transcription by a unique mechanism.

Authors:  G Nadeau; N Boufaied; A Moisan; K M Lemieux; C Cayanan; A N Monteiro; L Gaudreau
Journal:  EMBO Rep       Date:  2000-09       Impact factor: 8.807

Review 2.  Homologous DNA recombination in vertebrate cells.

Authors:  E Sonoda; M Takata; Y M Yamashita; C Morrison; S Takeda
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-17       Impact factor: 11.205

3.  Tumorigenesis in mice carrying a truncating Brca1 mutation.

Authors:  T Ludwig; P Fisher; S Ganesan; A Efstratiadis
Journal:  Genes Dev       Date:  2001-05-15       Impact factor: 11.361

4.  JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.

Authors:  Yan-Fen Hu; Rong Li
Journal:  Genes Dev       Date:  2002-06-15       Impact factor: 11.361

Review 5.  Emerging roles of BRCA1 alternative splicing.

Authors:  T I Orban; E Olah
Journal:  Mol Pathol       Date:  2003-08

Review 6.  Fine tuning chemotherapy to match BRCA1 status.

Authors:  Melissa Price; Alvaro N A Monteiro
Journal:  Biochem Pharmacol       Date:  2010-05-25       Impact factor: 5.858

7.  BRCA1 and BRCA2 in breast cancer predisposition and recombination control.

Authors:  Ralph Scully; Anyong Xie
Journal:  J Mammary Gland Biol Neoplasia       Date:  2004-07       Impact factor: 2.673

8.  Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability.

Authors:  Ellen E McCarthy; Julide T Celebi; Richard Baer; Thomas Ludwig
Journal:  Mol Cell Biol       Date:  2003-07       Impact factor: 4.272

9.  Assessment of functional effects of unclassified genetic variants.

Authors:  Fergus J Couch; Lene Juel Rasmussen; Robert Hofstra; Alvaro N A Monteiro; Marc S Greenblatt; Niels de Wind
Journal:  Hum Mutat       Date:  2008-11       Impact factor: 4.878

10.  Analysis of a set of missense, frameshift, and in-frame deletion variants of BRCA1.

Authors:  Marcelo Carvalho; Maria A Pino; Rachel Karchin; Jennifer Beddor; Martha Godinho-Netto; Rafael D Mesquita; Renato S Rodarte; Danielle C Vaz; Viviane A Monteiro; Siranoush Manoukian; Mara Colombo; Carla B Ripamonti; Richard Rosenquist; Graeme Suthers; Ake Borg; Paolo Radice; Scott A Grist; Alvaro N A Monteiro; Blase Billack
Journal:  Mutat Res       Date:  2008-10-17       Impact factor: 2.433

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