Literature DB >> 11048655

Toxoplasma gondii Hsp70 as a danger signal in toxoplasma gondii-infected mice.

H S Mun1, F Aosai, K Norose, M Chen, H Hata, Y I Tagawa, Y Iwakura, D S Byun, A Yano.   

Abstract

Toxoplasma gondii Hsp70, T gondii Hsp30/bag1, and surface antigen 1 messenger RNAs were shown to be useful in analyzing stage conversion of T gondii between bradyzoites and tachyzoites. The high-level expression of T gondii Hsp70 was correlated with mortality in interferon-gamma knockout mice infected with T gondii. Tgondii Hsp70 inhibited the induction of nitric oxide release by peritoneal macrophages of T gondii-infected mice. These findings identify T gondii Hsp70 as a danger signal during lethal, acute T gondii infection.

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Year:  2000        PMID： 11048655      PMCID： PMC312862          DOI： 10.1379/1466-1268(2000)005<0328:tghaad>2.0.co;2

Source DB:  PubMed          Journal:  Cell Stress Chaperones        ISSN： 1355-8145            Impact factor:   3.667


  26 in total

1.  Expression of Toxoplasma gondii-specific heat shock protein 70 during In vivo conversion of bradyzoites to tachyzoites.

Authors:  N M Silva; R T Gazzinelli; D A Silva; E A Ferro; L H Kasper; J R Mineo
Journal:  Infect Immun       Date:  1998-08       Impact factor: 3.441

2.  Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii.

Authors:  J L Burg; D Perelman; L H Kasper; P L Ware; J C Boothroyd
Journal:  J Immunol       Date:  1988-11-15       Impact factor: 5.422

3.  Toxoplasma gondii: difference of invasion into tissue of digestive organs between susceptible and resistant strain and influence of IFN-gamma in mice inoculated with the cysts perorally.

Authors:  M Kobayashi; F Aosai; H Hata; H S Mun; Y Tagawa; Y Iwakura; A Yano
Journal:  J Parasitol       Date:  1999-10       Impact factor: 1.276

4.  Common and divergent peptide binding specificities of hsp70 molecular chaperones.

Authors:  A M Fourie; J F Sambrook; M J Gething
Journal:  J Biol Chem       Date:  1994-12-02       Impact factor: 5.157

5.  Suppression of concanavalin A-induced hepatitis in IFN-gamma(-/-) mice, but not in TNF-alpha(-/-) mice: role for IFN-gamma in activating apoptosis of hepatocytes.

Authors:  Y Tagawa; K Sekikawa; Y Iwakura
Journal:  J Immunol       Date:  1997-08-01       Impact factor: 5.422

6.  Reduced replication of Toxoplasma gondii is necessary for induction of bradyzoite-specific antigens: a possible role for nitric oxide in triggering stage conversion.

Authors:  W Bohne; J Heesemann; U Gross
Journal:  Infect Immun       Date:  1994-05       Impact factor: 3.441

7.  Studies on the role of interleukin-12 in acute murine toxoplasmosis.

Authors:  C A Hunter; E Candolfi; C Subauste; V Van Cleave; J S Remington
Journal:  Immunology       Date:  1995-01       Impact factor: 7.397

8.  Induction of bradyzoite-specific Toxoplasma gondii antigens in gamma interferon-treated mouse macrophages.

Authors:  W Bohne; J Heesemann; U Gross
Journal:  Infect Immun       Date:  1993-03       Impact factor: 3.441

9.  Cloning and characterization of a bradyzoite-specifically expressed gene (hsp30/bag1) of Toxoplasma gondii, related to genes encoding small heat-shock proteins of plants.

Authors:  W Bohne; U Gross; D J Ferguson; J Heesemann
Journal:  Mol Microbiol       Date:  1995-06       Impact factor: 3.501

10.  Emergence of NK1.1+ cells as effectors of IFN-gamma dependent immunity to Toxoplasma gondii in MHC class I-deficient mice.

Authors:  E Y Denkers; R T Gazzinelli; D Martin; A Sher
Journal:  J Exp Med       Date:  1993-11-01       Impact factor: 14.307
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  13 in total

1.  Molecular cloning and characterization of a cytosolic heat shock protein 70 from Naegleria fowleri.

Authors:  Kyoung-Ju Song; Kyung-Hui Song; Byoung-Kuk Na; Jong-Hyun Kim; Daeho Kwon; Sun Park; Jhang-Ho Pak; Kyung-Il Im; Ho-Joon Shin
Journal:  Parasitol Res       Date:  2007-01-25       Impact factor: 2.289

2.  Cryptococcal heat shock protein 70 homolog Ssa1 contributes to pulmonary expansion of Cryptococcus neoformans during the afferent phase of the immune response by promoting macrophage M2 polarization.

Authors:  Alison J Eastman; Xiumiao He; Yafeng Qiu; Michael J Davis; Priya Vedula; Daniel M Lyons; Yoon-Dong Park; Sarah E Hardison; Antoni N Malachowski; John J Osterholzer; Floyd L Wormley; Peter R Williamson; Michal A Olszewski
Journal:  J Immunol       Date:  2015-05-13       Impact factor: 5.422

3.  Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derived heat shock protein 70.

Authors:  Hye-Seong Mun; Fumie Aosai; Kazumi Norose; Lian-Xun Piao; Hao Fang; Shizuo Akira; Akihiko Yano
Journal:  Infect Immun       Date:  2005-08       Impact factor: 3.441

4.  Toxoplasma gondii-derived heat shock protein 70 stimulates maturation of murine bone marrow-derived dendritic cells via Toll-like receptor 4.

Authors:  Fumie Aosai; Martha S Rodriguez Pena; Hye-Seong Mun; Hao Fang; Tetsuya Mitsunaga; Kazumi Norose; Hyun Kyu Kang; Yoe-Sik Bae; Akihiko Yano
Journal:  Cell Stress Chaperones       Date:  2006       Impact factor: 3.667

5.  Toxoplasma gondii infection inhibits Th17-mediated spontaneous development of arthritis in interleukin-1 receptor antagonist-deficient mice.

Authors:  Takuya Washino; Masataka Moroda; Yoichiro Iwakura; Fumie Aosai
Journal:  Infect Immun       Date:  2012-01-30       Impact factor: 3.441

6.  Effect of manganese on heat stress protein synthesis of new-born rats.

Authors:  Ben-Yan Zhang; Sheng Chen; Fang-Li Ye; Chang-Cai Zhu; He-Xi Zhang; Rui-Bo Wang; Cheng-Fen Xiao; Tang-Chun Wu; Guo-Gao Zhang
Journal:  World J Gastroenterol       Date:  2002-02       Impact factor: 5.742

7.  Heat shock protein 70 of Naegleria fowleri is important factor for proliferation and in vitro cytotoxicity.

Authors:  Kyoung-Ju Song; Kyung-Hui Song; Jong-Hyun Kim; Hae-Jin Sohn; Yang-Jin Lee; Chang-Eun Park; Ho-Joon Shin
Journal:  Parasitol Res       Date:  2008-04-18       Impact factor: 2.289

8.  Interleukin-17A-Deficient Mice Are Highly Susceptible to Toxoplasma gondii Infection Due to Excessively Induced T. gondii HSP70 and Interferon Gamma Production.

Authors:  Masataka Moroda; Masaya Takamoto; Yoichiro Iwakura; Jun Nakayama; Fumie Aosai
Journal:  Infect Immun       Date:  2017-11-17       Impact factor: 3.441

9.  Toxoplasma gondii-derived heat shock protein HSP70 functions as a B cell mitogen.

Authors:  Fumie Aosai; Mei Chen; Hyun-Kyu Kang; Hye-Seong Mun; Kazumi Norose; Lian Xun Piao; Masashi Kobayashi; Osamu Takeuchi; Shizuo Akira; Akihiko Yano
Journal:  Cell Stress Chaperones       Date:  2002-10       Impact factor: 3.667

10.  Toxoplasma gondii 70 kDa heat shock protein: systemic detection is associated with the death of the parasites by the immune response and its increased expression in the brain is associated with parasite replication.

Authors:  Paulo Victor Czarnewski Barenco; Elaine Vicente Lourenço; Jair Pereira Cunha-Júnior; Karine Cristine Almeida; Maria Cristina Roque-Barreira; Deise Aparecida Oliveira Silva; Ester Cristina Borges Araújo; Loyane Bertagnolli Coutinho; Mário Cézar Oliveira; Tiago Wilson Patriarca Mineo; José Roberto Mineo; Neide Maria Silva
Journal:  PLoS One       Date:  2014-05-06       Impact factor: 3.240
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