Literature DB >> 8432596

Induction of bradyzoite-specific Toxoplasma gondii antigens in gamma interferon-treated mouse macrophages.

W Bohne1, J Heesemann, U Gross.   

Abstract

By using stage-specific monoclonal antibodies, an in vitro model has been developed to analyze the kinetics of expression of stage-specific antigens during the conversion process between tachyzoites and bradyzoites of Toxoplasma gondii. Following infection of murine macrophages with bradyzoites, the expression of bradyzoite-specific antigens declined, whereas the expression of tachyzoite-specific antigens increased during the first 72 h postinfection. Conversely, in gamma interferon-treated murine macrophages infected with tachyzoites, the inhibitory effect of gamma interferon on replication of parasites was accompanied by the induction of bradyzoite-specific antigens.

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Year:  1993        PMID： 8432596      PMCID： PMC302852          DOI： 10.1128/iai.61.3.1141-1145.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  28 in total

1.  Characterization of bradyzoite-specific antigens of Toxoplasma gondii.

Authors:  S Tomavo; B Fortier; M Soete; C Ansel; D Camus; J F Dubremetz
Journal:  Infect Immun       Date:  1991-10       Impact factor: 3.441

2.  Role of TNF and IL-1 in infections with Toxoplasma gondii.

Authors:  H R Chang; G E Grau; J C Pechère
Journal:  Immunology       Date:  1990-01       Impact factor: 7.397

3.  IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alpha.

Authors:  J A Langermans; M E Van der Hulst; P H Nibbering; P S Hiemstra; L Fransen; R Van Furth
Journal:  J Immunol       Date:  1992-01-15       Impact factor: 5.422

4.  Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine.

Authors:  L B Adams; J B Hibbs; R R Taintor; J L Krahenbuhl
Journal:  J Immunol       Date:  1990-04-01       Impact factor: 5.422

5.  Toxoplasma gondii: antigenic differences between endozoites and cystozoites defined by monoclonal antibodies.

Authors:  Y Omata; M Igarashi; M I Ramos; T Nakabayashi
Journal:  Parasitol Res       Date:  1989       Impact factor: 2.289

6.  Importance of endogenous IFN-gamma for prevention of toxoplasmic encephalitis in mice.

Authors:  Y Suzuki; F K Conley; J S Remington
Journal:  J Immunol       Date:  1989-09-15       Impact factor: 5.422

7.  Identification of a virulence-associated antigen of Toxoplasma gondii by use of a mouse monoclonal antibody.

Authors:  U Gross; W A Müller; S Knapp; J Heesemann
Journal:  Infect Immun       Date:  1991-12       Impact factor: 3.441

8.  Human endothelial cells are activated by IFN-gamma to inhibit Toxoplasma gondii replication. Inhibition is due to a different mechanism from that existing in mouse macrophages and human fibroblasts.

Authors:  J P Woodman; I H Dimier; D T Bout
Journal:  J Immunol       Date:  1991-09-15       Impact factor: 5.422

9.  Tumor necrosis factor-alpha triggers antitoxoplasmal activity of IFN-gamma primed macrophages.

Authors:  L D Sibley; L B Adams; Y Fukutomi; J L Krahenbuhl
Journal:  J Immunol       Date:  1991-10-01       Impact factor: 5.422

Review 10.  Role of gamma interferon in Toxoplasma gondii infection.

Authors:  C S Subauste; J S Remington
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-02       Impact factor: 3.267
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  52 in total

Review 1.  The development and biology of bradyzoites of Toxoplasma gondii.

Authors:  L M Weiss; K Kim
Journal:  Front Biosci       Date:  2000-04-01

2.  Disruption of the Toxoplasma gondii bradyzoite-specific gene BAG1 decreases in vivo cyst formation.

Authors:  Y W Zhang; K Kim; Y F Ma; M Wittner; H B Tanowitz; L M Weiss
Journal:  Mol Microbiol       Date:  1999-01       Impact factor: 3.501

3.  Disruption of a locus encoding a nucleolar zinc finger protein decreases tachyzoite-to-bradyzoite differentiation in Toxoplasma gondii.

Authors:  Padmini Vanchinathan; Jeremy L Brewer; Omar S Harb; John C Boothroyd; Upinder Singh
Journal:  Infect Immun       Date:  2005-10       Impact factor: 3.441

4.  A patatin-like protein protects Toxoplasma gondii from degradation in activated macrophages.

Authors:  Dana G Mordue; Casey F Scott-Weathers; Crystal M Tobin; Laura J Knoll
Journal:  Mol Microbiol       Date:  2006-12-11       Impact factor: 3.501

5.  Toxoplasma gondii strains defective in oral transmission are also defective in developmental stage differentiation.

Authors:  Blima Fux; Julie Nawas; Asis Khan; Darcy B Gill; Chunlei Su; L David Sibley
Journal:  Infect Immun       Date:  2007-03-05       Impact factor: 3.441

Review 6.  The molecular biology and immune control of chronic Toxoplasma gondii infection.

Authors:  Xiao-Yu Zhao; Sarah E Ewald
Journal:  J Clin Invest       Date:  2020-07-01       Impact factor: 14.808

7.  Toxoplasma gondii cyclophilin 18-mediated production of nitric oxide induces Bradyzoite conversion in a CCR5-dependent manner.

Authors:  Hany M Ibrahim; Hiroshi Bannai; Xuenan Xuan; Yoshifumi Nishikawa
Journal:  Infect Immun       Date:  2009-06-29       Impact factor: 3.441

8.  Expression of Toxoplasma gondii-specific heat shock protein 70 during In vivo conversion of bradyzoites to tachyzoites.

Authors:  N M Silva; R T Gazzinelli; D A Silva; E A Ferro; L H Kasper; J R Mineo
Journal:  Infect Immun       Date:  1998-08       Impact factor: 3.441

9.  Bradyzoite development in Toxoplasma gondii and the hsp70 stress response.

Authors:  L M Weiss; Y F Ma; P M Takvorian; H B Tanowitz; M Wittner
Journal:  Infect Immun       Date:  1998-07       Impact factor: 3.441

10.  Different roles for interleukin-4 during the course of Toxoplasma gondii infection.

Authors:  C W Roberts; D J Ferguson; H Jebbari; A Satoskar; H Bluethmann; J Alexander
Journal:  Infect Immun       Date:  1996-03       Impact factor: 3.441
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