Literature DB >> 11048474

[Proposal of a new test for the diagnosis of PROM based on the determination of hCG in the washing fluid of the posterior vaginal fornix].

B Mangano1, F Diani, G Faccini, N Zatti, E Zardini.   

Abstract

BACKGROUND: The objective of this study is to determine whether or not the measurement of hCG levels in the washing fluid of the posterior vaginal fornix is useful for the diagnosis of premature rupture of membranes.
METHODS: Samples were analysed from 52 normal pregnant women, divided into three groups: 20 pregnant women without rupture of membranes, 21 patients with confirmed rupture of membranes, 11 patients with suspected rupture of membranes. In order to distinguish patients of the two groups we propose a hCG cut-off value of 100 mIU/ml.
RESULTS: The analysis of our data reveals that there is no overlapping between the hCG levels of the group of pregnant women without rupture of membranes and the group of patients with confirmed rupture of membranes.
CONCLUSIONS: The hCG levels in the washing fluid of the posterior vaginal fornix in our experience is a useful, very cheap and non-invasive diagnostic test of PROM.

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Year:  2000        PMID: 11048474

Source DB:  PubMed          Journal:  Minerva Ginecol        ISSN: 0026-4784


  2 in total

1.  β-human chorionic gonadotropin assay in vaginal washing fluid for the accurate diagnosis of premature rupture of membranes during late pregnancy.

Authors:  Orhan Temel; Ebru Cöğendez; Selçuk Selçuk; Mehmet Reşit Asoğlu; Erdal Kaya
Journal:  J Turk Ger Gynecol Assoc       Date:  2013-12-01

2.  Use of cervicovaginal fluid for the identification of biomarkers for pathologies of the female genital tract.

Authors:  Geert Zegels; Geert Aa Van Raemdonck; Wiebren Aa Tjalma; Xaveer Wm Van Ostade
Journal:  Proteome Sci       Date:  2010-12-08       Impact factor: 2.480

  2 in total

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