Literature DB >> 1104207

The orthomolecular treatment of cancer. III. Reticulum cell sarcoma: double complete regression induced by high-dose ascorbic acid therapy.

E Cameron, A Campbell, T Jack.   

Abstract

The response of a patient with histologically proven reticulum cell sarcoma to no treatment other than large doses of ascorbic acid is described. At the time of first diagnosis, the disease was widely disseminated, and a very dramatic regression of all parameters of disease activity was induced by the continuous administration of large doses of ascorbic acid. Reduction in dosage some months later coincided with reactivation of the disease process. The reinstitution of regular high-dose ascorbic acid therapy induced a second complete remission. The case report is illustrated by serial radiographs. The significance of the therapeutic response is briefly discussed in relation to general schemes of cancer management.

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Year:  1975        PMID: 1104207     DOI: 10.1016/0009-2797(75)90007-1

Source DB:  PubMed          Journal:  Chem Biol Interact        ISSN: 0009-2797            Impact factor:   5.192


  29 in total

1.  Proof versus plausibility: rules of engagement for the struggle to evaluate alternative cancer therapies.

Authors:  L J Hoffer
Journal:  CMAJ       Date:  2001-02-06       Impact factor: 8.262

Review 2.  Ascorbic acid: chemistry, biology and the treatment of cancer.

Authors:  Juan Du; Joseph J Cullen; Garry R Buettner
Journal:  Biochim Biophys Acta       Date:  2012-06-20

3.  Intravenously administered vitamin C as cancer therapy: three cases.

Authors:  Sebastian J Padayatty; Hugh D Riordan; Stephen M Hewitt; Arie Katz; L John Hoffer; Mark Levine
Journal:  CMAJ       Date:  2006-03-28       Impact factor: 8.262

Review 4.  Parenteral ascorbate as a cancer therapeutic: a reassessment based on pharmacokinetics.

Authors:  Nermi L Parrow; Jonathan A Leshin; Mark Levine
Journal:  Antioxid Redox Signal       Date:  2013-06-19       Impact factor: 8.401

Review 5.  Ascorbic Acid in Cancer Treatment: Let the Phoenix Fly.

Authors:  Niraj Shenoy; Edward Creagan; Thomas Witzig; Mark Levine
Journal:  Cancer Cell       Date:  2018-08-30       Impact factor: 31.743

Review 6.  Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries.

Authors:  Mark Levine; Sebastian J Padayatty; Michael Graham Espey
Journal:  Adv Nutr       Date:  2011-03-10       Impact factor: 8.701

7.  Inhibition of benzo(a)pyrene carcinogenesis in rats with vitamin C.

Authors:  G Kallistratos; E Fasske
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553

8.  Effects of intake of L-ascorbic acid on the incidence of dermal neoplasms induced in mice by ultraviolet light.

Authors:  W B Dunham; E Zuckerkandl; R Reynolds; R Willoughby; R Marcuson; R Barth; L Pauling
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

Review 9.  Vitamin C: update on physiology and pharmacology.

Authors:  J Mandl; A Szarka; G Bánhegyi
Journal:  Br J Pharmacol       Date:  2009-06-05       Impact factor: 8.739

10.  Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer.

Authors:  E Cameron; L Pauling
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

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