Literature DB >> 11041403

Transmission of BSE by blood transfusion in sheep.

F Houston, J D Foster, A Chong, N Hunter, C J Bostock.   

Abstract

We have shown that it is possible to transmit bovine spongiform encephalopathy (BSE) to a sheep by transfusion with whole blood taken from another sheep during the symptom-free phase of an experimental BSE infection. BSE and variant Creutzfeldt-Jakob disease (vCJD) In human beings are caused by the same infectious agent, and the sheep-BSE experimental model has a similar pathogenesis to that of human vCJD. Although UK blood transfusions are leucodepleted--a possible protective measure against any risk from blood transmission--this report suggests that blood donated by symptom-free vCJD-infected human beings may represent a risk of spread of vCJD infection among the human population of the UK.

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Year:  2000        PMID： 11041403     DOI： 10.1016/s0140-6736(00)02719-7

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  91 in total

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Authors:  A Bencsik; S Lezmi; T Baron
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2.  Peripheral prion pursuit.

Authors:  A Aguzzi
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3.  From nannyism to public disclosure: the BSE inquiry report.

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4.  Disease-associated prion protein in vessel walls.

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5.  Transmission of prions.

Authors:  C Weissmann; M Enari; P-C Klöhn; D Rossi; E Flechsig
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-14       Impact factor: 11.205

Review 6.  Blood transfusion medicine.

Authors:  Fiona Regan; Clare Taylor
Journal:  BMJ       Date:  2002-07-20

7.  Prionemia and leukocyte-platelet-associated infectivity in sheep transmissible spongiform encephalopathy models.

Authors:  Caroline Lacroux; Didier Vilette; Natalia Fernández-Borges; Claire Litaise; Séverine Lugan; Nathalie Morel; Fabien Corbière; Stéphanie Simon; Hugh Simmons; Pierrette Costes; Jean-Louis Weisbecker; Isabelle Lantier; Frederic Lantier; François Schelcher; Jacques Grassi; Joaquin Castilla; Olivier Andréoletti
Journal:  J Virol       Date:  2011-12-07       Impact factor: 5.103

Review 8.  Cell salvage for minimising perioperative allogeneic blood transfusion.

Authors:  Paul A Carless; David A Henry; Annette J Moxey; Dianne O'Connell; Tamara Brown; Dean A Fergusson
Journal:  Cochrane Database Syst Rev       Date:  2010-04-14

9.  Report of the Working Group 'Overall Blood Supply Strategy with Regard to Variant Creutzfeldt-Jakob Disease (vCJD)': Statement on the Development and Implementation of Test Systems Suitable for the Screening of Blood Donors for vCJD - Dated September 17, 2008.

Authors: 
Journal:  Transfus Med Hemother       Date:  2009       Impact factor: 3.747

10.  Reduction of prion infectivity in packed red blood cells.

Authors:  Rodrigo Morales; Kimberley A Buytaert-Hoefen; Dennisse Gonzalez-Romero; Joaquin Castilla; Eric T Hansen; Dennis Hlavinka; Raymond P Goodrich; Claudio Soto
Journal:  Biochem Biophys Res Commun       Date:  2008-10-11       Impact factor: 3.575
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