Literature DB >> 11034333

Inteins invading mycobacterial RecA proteins.

I Saves1, M A Lanéelle, M Daffé, J M Masson.   

Abstract

Five new inteins were discovered in a survey of 39 mycobacterial strains that was undertaken to clarify the role of RecA inteins in mycobacteria. They are all inserted at the RecA-b site of the recA gene of Mycobacterium chitae, 4. fallax, M. gastri, M. shimodei and M. thermoresistibile and belong to the MleRecA allelic family. Sequence analysis showed that although only M. tuberculosis harbours an intein at the RecA-a site the sequence of the RecA-b site is well conserved between species. Furthermore, the presence of inteins does not correlate with specific characteristics of the species such as pathogenicity or growth rate.

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Year:  2000        PMID： 11034333     DOI： 10.1016/s0014-5793(00)01944-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  9 in total

1.  Identification of the first eubacterial endonuclease coded by an intein allele in the pps1 gene of mycobacteria.

Authors:  I Saves; F Westrelin; M Daffé; J M Masson
Journal:  Nucleic Acids Res       Date:  2001-11-01       Impact factor: 16.971

2.  Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.

Authors:  Athanasios Lykidis; Konstantinos Mavromatis; Natalia Ivanova; Iain Anderson; Miriam Land; Genevieve DiBartolo; Michele Martinez; Alla Lapidus; Susan Lucas; Alex Copeland; Paul Richardson; David B Wilson; Nikos Kyrpides
Journal:  J Bacteriol       Date:  2007-01-05       Impact factor: 3.490

3.  Specificities and functions of the recA and pps1 intein genes of Mycobacterium tuberculosis and application for diagnosis of tuberculosis.

Authors:  Isabelle Saves; Lee-Ann Lewis; Fabrice Westrelin; Robin Warren; Mamadou Daffé; Jean-Michel Masson
Journal:  J Clin Microbiol       Date:  2002-03       Impact factor: 5.948

4.  Identification of the Mycobacterium tuberculosis SUF machinery as the exclusive mycobacterial system of [Fe-S] cluster assembly: evidence for its implication in the pathogen's survival.

Authors:  Gaëlle Huet; Mamadou Daffé; Isabelle Saves
Journal:  J Bacteriol       Date:  2005-09       Impact factor: 3.490

5.  Characterization of Mycobacterium leprae RecA intein, a LAGLIDADG homing endonuclease, reveals a unique mode of DNA binding, helical distortion, and cleavage compared with a canonical LAGLIDADG homing endonuclease.

Authors:  Pawan Singh; Pankaj Tripathi; George H Silva; Alfred Pingoud; K Muniyappa
Journal:  J Biol Chem       Date:  2009-07-15       Impact factor: 5.157

6.  Distribution of split DnaE inteins in cyanobacteria.

Authors:  Jonathan Caspi; Gil Amitai; Olga Belenkiy; Shmuel Pietrokovski
Journal:  Mol Microbiol       Date:  2003-12       Impact factor: 3.501

7.  Group I self-splicing intron in the recA gene of Bacillus anthracis.

Authors:  Minsu Ko; Hyang Choi; Chankyu Park
Journal:  J Bacteriol       Date:  2002-07       Impact factor: 3.490

8.  ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family.

Authors:  Alberto I Roca; Albert E Almada; Aaron C Abajian
Journal:  BMC Bioinformatics       Date:  2008-12-22       Impact factor: 3.169

Review 9.  Intein Inhibitors as Novel Antimicrobials: Protein Splicing in Human Pathogens, Screening Methods, and Off-Target Considerations.

Authors:  Diana A Wall; Seanan P Tarrant; Chunyu Wang; Kenneth V Mills; Christopher W Lennon
Journal:  Front Mol Biosci       Date:  2021-10-07
  9 in total

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