Literature DB >> 11030299

Treatment of solid tumours in children with tumour-lysate-pulsed dendritic cells.

J Geiger, R Hutchinson, L Hohenkirk, E McKenna, A Chang, J Mulé.   

Abstract

Dendritic cells are potent stimulators of antigen-specific immune responses, including antitumour responses. We explored the use of tumour-lysate-pulsed dendritic cells in children with relapsed solid tumours. Dendritic cell treatment in children was feasible and apparently not toxic. The treatment was able to produce significant tumour regression in a child with metastatic fibrosarcoma.

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Year:  2000        PMID: 11030299     DOI: 10.1016/S0140-6736(00)02762-8

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  27 in total

1.  Quantification of antigen-reactive T cells by a modified ELISPOT assay based on freshly isolated blood dendritic cells.

Authors:  M Schmitz; J Rohayem; R Paul; B Weigle; A Stein; E P Rieber
Journal:  J Clin Lab Anal       Date:  2002       Impact factor: 2.352

2.  Dendritic cells, pulsed with lysate of allogeneic tumor cells, are capable of stimulating MHC-restricted antigen-specific antitumor T cells.

Authors:  Reza Mahdian; Parviz Kokhaei; Hossein Motieian Najar; Katja Derkow; Aniruddha Choudhury; Håkan Mellstedt
Journal:  Med Oncol       Date:  2006       Impact factor: 3.064

3.  Melanoma vaccines: clinical status and immune endpoints.

Authors:  Deena M Maurer; Lisa H Butterfield; Lazar Vujanovic
Journal:  Melanoma Res       Date:  2019-04       Impact factor: 3.599

Review 4.  Exploiting dendritic cells for active immunotherapy of cancer and chronic infections.

Authors:  David W O'Neill; Nina Bhardwaj
Journal:  Mol Biotechnol       Date:  2007-06       Impact factor: 2.695

Review 5.  Cryoimmunology for malignant bone and soft-tissue tumors.

Authors:  Hideji Nishida; Norio Yamamoto; Yoshikazu Tanzawa; Hiroyuki Tsuchiya
Journal:  Int J Clin Oncol       Date:  2011-03-12       Impact factor: 3.402

Review 6.  Dendritic cell vaccines: A review of recent developments and their potential pediatric application.

Authors:  Jennifer D Elster; Deepa K Krishnadas; Kenneth G Lucas
Journal:  Hum Vaccin Immunother       Date:  2016-05-31       Impact factor: 3.452

Review 7.  Immunotherapy in pediatric malignancies: current status and future perspectives.

Authors:  Christian M Capitini; Mario Otto; Kenneth B DeSantes; Paul M Sondel
Journal:  Future Oncol       Date:  2014       Impact factor: 3.404

Review 8.  Immunotherapy of childhood cancer: from biologic understanding to clinical application.

Authors:  Alan S Wayne; Christian M Capitini; Crystal L Mackall
Journal:  Curr Opin Pediatr       Date:  2010-02       Impact factor: 2.856

Review 9.  Immune-based therapeutics for pediatric cancer.

Authors:  Christian M Capitini; Crystal L Mackall; Alan S Wayne
Journal:  Expert Opin Biol Ther       Date:  2010-02       Impact factor: 4.388

Review 10.  Dendritic cell-based combined immunotherapy with autologous tumor-pulsed dendritic cell vaccine and activated T cells for cancer patients: rationale, current progress, and perspectives.

Authors:  Takashi Morisaki; Kotaro Matsumoto; Hideya Onishi; Hideo Kuroki; Eishi Baba; Akira Tasaki; Makoto Kubo; Mitsunari Nakamura; Syoichi Inaba; Koji Yamaguchi; Masao Tanaka; Mitsuo Katano
Journal:  Hum Cell       Date:  2003-12       Impact factor: 4.174

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