| Literature DB >> 17914192 |
David W O'Neill1, Nina Bhardwaj.
Abstract
Dendritic cells (DCs) are important antigen-presenting cells (APCs) that can prime naive T cells and control adaptive immune responses with respect to magnitude, memory and self-tolerance. Understanding the biology of these cells is central to the development of new generation immunotherapies for cancer and chronic infections. This review presents a brief overview of DC biology and of the preparation and use of DC-based vaccines.Entities:
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Year: 2007 PMID: 17914192 DOI: 10.1007/s12033-007-0020-6
Source DB: PubMed Journal: Mol Biotechnol ISSN: 1073-6085 Impact factor: 2.695