OBJECTIVES: This study assessed the association of dietary folate, vitamin B6, and vitamin B12 with cardiovascular mortality. METHODS: Poisson regression analyses assessed coronary/cerebrovascular mortality rates via nutrient data obtained from the National Nutrition Survey, which recorded 7-day food intakes from a national sample of 21,155 households. RESULTS: In regard to coronary mortality, male and female rate ratios (highest vs lowest quintile) were 0.83 (95% confidence interval [CI] = 0.77, 0.91) and 0.95 (95% CI = 0.86, 1.05), respectively, for folate and 0.74 (95% CI = 0.65, 0.84) and 0.86 (95% CI = 0.73, 0.99), respectively, for B12. Intake of folate and B6 (but not B12) was significantly associated with cerebrovascular mortality. CONCLUSIONS: B vitamins are associated with cardiovascular mortality in the general population.
OBJECTIVES: This study assessed the association of dietary folate, vitamin B6, and vitamin B12 with cardiovascular mortality. METHODS: Poisson regression analyses assessed coronary/cerebrovascular mortality rates via nutrient data obtained from the National Nutrition Survey, which recorded 7-day food intakes from a national sample of 21,155 households. RESULTS: In regard to coronary mortality, male and female rate ratios (highest vs lowest quintile) were 0.83 (95% confidence interval [CI] = 0.77, 0.91) and 0.95 (95% CI = 0.86, 1.05), respectively, for folate and 0.74 (95% CI = 0.65, 0.84) and 0.86 (95% CI = 0.73, 0.99), respectively, for B12. Intake of folate and B6 (but not B12) was significantly associated with cerebrovascular mortality. CONCLUSIONS: B vitamins are associated with cardiovascular mortality in the general population.
Authors: K J Joshipura; A Ascherio; J E Manson; M J Stampfer; E B Rimm; F E Speizer; C H Hennekens; D Spiegelman; W C Willett Journal: JAMA Date: 1999-10-06 Impact factor: 56.272
Authors: J Selhub; P F Jacques; A G Bostom; R B D'Agostino; P W Wilson; A J Belanger; D H O'Leary; P A Wolf; E J Schaefer; I H Rosenberg Journal: N Engl J Med Date: 1995-02-02 Impact factor: 91.245
Authors: P Verhoef; M J Stampfer; J E Buring; J M Gaziano; R H Allen; S P Stabler; R D Reynolds; F J Kok; C H Hennekens; W C Willett Journal: Am J Epidemiol Date: 1996-05-01 Impact factor: 4.897
Authors: María José Medrano; Raquel Boix; Alba Palmera; Rebeca Ramis; Iñaki Galán; Gonzalo López-Abente Journal: BMC Public Health Date: 2012-03-09 Impact factor: 3.295
Authors: Jesús de Pedro-Cuesta; Javier Virués-Ortega; Saturio Vega; Manuel Seijo-Martínez; Pedro Saz; Fernanda Rodríguez; Angel Rodríguez-Laso; Ramón Reñé; Susana Pérez de las Heras; Raimundo Mateos; Pablo Martínez-Martín; José María Manubens; Ignacio Mahillo-Fernandez; Secundino López-Pousa; Antonio Lobo; Jordi Llinàs Reglà; Jordi Gascón; Francisco José García; Manuel Fernández-Martínez; Raquel Boix; Félix Bermejo-Pareja; Alberto Bergareche; Julián Benito-León; Ana de Arce; José Luis del Barrio Journal: BMC Neurol Date: 2009-10-19 Impact factor: 2.474