Literature DB >> 1102612

The L.A.I. microtest: a rapid and sensitive precedure for the demonstration of cell-mediated immunity in vitro.

P G Holt, L M Roberts, P J Fimmel, D Keast.   

Abstract

A new microtest for cell-mediated immunity is described, which is based on the elaboration of a diffusible factor from sensitized lymphocytes following contact with specific antigen. The factor inhibits the adherence of neighbouring leucocytes to plastic surfaces. Production of the factor is ablated by pretreatment of lymphocytes with Theta-antiserum. It is suggested that the factor may be a new lymphokine, leucocyte adherence inhibition factor (LAIF).

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Year:  1975        PMID: 1102612     DOI: 10.1016/0022-1759(75)90122-2

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN: 0022-1759            Impact factor:   2.303


  13 in total

1.  Serum modulation of in vitro cellular immune reactivity to Epstein-Barr virus-associated antigen.

Authors:  P G Holt; P J Fimmel; L M Roberts; D Keast
Journal:  Med Microbiol Immunol       Date:  1976-12-01       Impact factor: 3.402

2.  Cell-mediated immunity to bacterial flagellin as assessed by leucocyte adherence inhibition.

Authors:  J G Aaskov; W J Halliday
Journal:  Med Microbiol Immunol       Date:  1978-10-20       Impact factor: 3.402

3.  Comparison of a leucocyte adherence test with the leucocyte migration inhibition test and skin reactivity to PPD.

Authors:  A W Bullen; M S Losowsky
Journal:  Clin Exp Immunol       Date:  1978-03       Impact factor: 4.330

4.  Modification by soluble antigen of the immune response to mycobacterial infection.

Authors:  P G Holt; P J Fimmel; L M Roberts; D Keast
Journal:  Infect Immun       Date:  1977-06       Impact factor: 3.441

5.  Investigations on blood and cerebrospinal fluid lymphocytes in patients suffering from tick-borne encephalitis.

Authors:  J Sipos; P Ribiczey; V Gábor; Z Tóth; K Bartók
Journal:  Infection       Date:  1981       Impact factor: 3.553

6.  Cell populations in leucocyte adherence inhibition: requirement for T lymphocytes with IgG Fc receptors.

Authors:  A E Powell; R E Birch; H Murrell; A M Sloss
Journal:  Immunology       Date:  1982-08       Impact factor: 7.397

7.  Regulation of leukocyte glass adherence and tube leukocyte adherence inhibition (LAI) reactivity by serum factors in dogs with progressing or spontaneously regressing canine transmissible venereal sarcoma (CTVS).

Authors:  M W Harding; T J Yang
Journal:  Cancer Immunol Immunother       Date:  1985       Impact factor: 6.968

8.  Capillary tube leucocyte adherence inhibition assay for cell-mediated immunity: effects of transient bacterial infection in guinea-pigs.

Authors:  C M Ballard; J P Dickinson
Journal:  Clin Exp Immunol       Date:  1980-05       Impact factor: 4.330

9.  Studies of cellular mediated immunity in malignant melanoma patients by Leukocyte Adherence Inhibition Test.

Authors:  S Müller; T M Ernst
Journal:  Arch Dermatol Res       Date:  1980       Impact factor: 3.017

10.  Leucocyte adherence inhibition assay for cell-mediated immunity and immunodiagnosis of pancreatic cancer.

Authors:  M Onji
Journal:  Gastroenterol Jpn       Date:  1984-08
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