Literature DB >> 11020644

Left vagal nerve stimulation in six patients with hypothalamic hamartomas.

J V Murphy1, J W Wheless, C M Schmoll.   

Abstract

Six patients with medically refractory epilepsy secondary to hypothalamic hamartomas were treated with intermittent stimulation of the left vagal nerve. Three of the patients had remarkable improvements in seizure control. Four of these six patients had severe autistic behaviors. Striking improvements in these behaviors were observed in all four during treatment with intermittent stimulation. This finding suggests that vagal nerve stimulation can control seizures and autistic behaviors in patients with hypothalamic hamartomas.

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Year:  2000        PMID： 11020644     DOI： 10.1016/s0887-8994(00)00170-3

Source DB:  PubMed          Journal:  Pediatr Neurol        ISSN： 0887-8994            Impact factor:   3.372


  18 in total

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2.  Vagus nerve stimulation: effectiveness and tolerability in patients with epileptic encephalopathies.

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3.  Vagal nerve stimulation for pharmacoresistant epilepsy in children.

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5.  Autistic spectrum disorder, epilepsy, and vagus nerve stimulation.

Authors:  Mariam Mettry Hull; Deepak Madhavan; Charles M Zaroff
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Review 6.  Hypothalamic hamartomas--clinical, neuropathological and surgical aspects.

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Journal:  Childs Nerv Syst       Date:  2006-06-09       Impact factor: 1.475

7.  Pure endoscopic management of epileptogenic hypothalamic hamartomas.

Authors:  S Chibbaro; H Cebula; J Scholly; J Todeschi; I Ollivier; A Timofeev; M Ganau; P Di Emidio; M P Valenti; A M Staack; T Bast; B J Steinhoff; E Hirsch; P Kehrli; F Proust
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8.  Abnormal autonomic and associated brain activities during rest in autism spectrum disorder.

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Journal:  Brain       Date:  2014-01       Impact factor: 13.501

Review 9.  A review on the management of epilepsy associated with hypothalamic hamartomas.

Authors:  James L Frazier; C Rory Goodwin; Edward S Ahn; George I Jallo
Journal:  Childs Nerv Syst       Date:  2009-01-20       Impact factor: 1.475

Review 10.  Stimulation of the nervous system for the management of seizures: current and future developments.

Authors:  Jerome V Murphy; Arunangelo Patil
Journal:  CNS Drugs       Date:  2003       Impact factor: 5.749
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