| Literature DB >> 11018700 |
H R Siebner1, C Rossmeier, C Mentschel, A Peinemann, B Conrad.
Abstract
Ten unmedicated patients with Parkinson's disease received sub-threshold 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the primary motor hand area (M1(HAND)) contralaterally to the more affected upper limb. Compared to a midfrontal sham-rTMS, real-rTMS over M1(HAND) was associated with a significant decrease in the global motor UPDRS score 1 h after the cessation of rTMS. This was mainly due to a clinical improvement in the arm contralaterally to the stimulated M1(HAND). These preliminary data suggest that focal rTMS of M1(HAND) may have a therapeutic potential in PD.Entities:
Mesh:
Year: 2000 PMID: 11018700 DOI: 10.1016/s0022-510x(00)00370-1
Source DB: PubMed Journal: J Neurol Sci ISSN: 0022-510X Impact factor: 3.181