Literature DB >> 11003346

Solid organ transplantation: are there predictors for posttransplant noncompliance? A literature overview.

B Bunzel1, K Laederach-Hofmann.   

Abstract

BACKGROUND: Many studies confirm that noncompliance or poor compliance is one of the great problems in health care as it results in waste of resources and funds.
METHODS: This overview includes literature on heart, liver, and kidney transplants with emphasis on heart transplantation in adult and pediatric transplant patients and addresses the following variables as potential predictors of postoperative compliance problems: demographic variables (age, marital status, gender) psychological variables (anxiety, denial) psychiatric disorders (major depression, anxiety, and personality disorders), poor social support, pretransplant noncompliance, obesity, substance abuse, and health-related variables (distance from transplant center, indication for transplantation, required pretransplant assist device). Relevant studies on these topics that were conducted up to 1999 are included and discussed in this overview. The most important results are presented in tables.
RESULTS: Unfortunately, there has not been any systematic and comprehensive review of the literature on predictors of noncompliance in organ transplant patients so far. With organ transplantation noncompliance impairs both life quality and life span as it is a major risk factor for graft rejection episodes and is responsible for up to 25% of deaths after the initial recovery period. Therefore, it might be assumed that well-informed transplant patients are a highly motivated group whose compliance is just as high. This is not the case. However, even when graft loss means loss of life as in heart or liver transplantation, noncompliance occurs. To best select potential organ recipients, it would be ideal if patients who are very likely to show noncompliant behavior could be identified already before being transplanted.
CONCLUSION: The literature overview shows the necessity of preoperative psychosocial screening regarding predictors for posttransplant noncompliance.

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Mesh:

Year:  2000        PMID: 11003346     DOI: 10.1097/00007890-200009150-00001

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  22 in total

1.  Meta-analysis of risk for relapse to substance use after transplantation of the liver or other solid organs.

Authors:  Mary Amanda Dew; Andrea F DiMartini; Jennifer Steel; Annette De Vito Dabbs; Larissa Myaskovsky; Mark Unruh; Joel Greenhouse
Journal:  Liver Transpl       Date:  2008-02       Impact factor: 5.799

2.  Behavioral measures to reduce non-adherence in renal transplant recipients: a prospective randomized controlled trial.

Authors:  Márcia Fátima Faraldo Martinez Garcia; Ariane Moyses Bravin; Paula Dalsoglio Garcia; Mariana Moraes Contti; Hong Si Nga; Henrique Mochida Takase; Luis Gustavo Modelli de Andrade
Journal:  Int Urol Nephrol       Date:  2015-09-16       Impact factor: 2.370

Review 3.  Enteric-coated mycophenolate sodium: tolerability profile compared with mycophenolate mofetil.

Authors:  Matthias Behrend; Felix Braun
Journal:  Drugs       Date:  2005       Impact factor: 9.546

4.  Patient-reported immunosuppression nonadherence 6 to 24 months after liver transplant: association with pretransplant psychosocial factors and perceptions of health status change.

Authors:  James R Rodrigue; David R Nelson; Douglas W Hanto; Alan I Reed; Michael P Curry
Journal:  Prog Transplant       Date:  2013-12       Impact factor: 1.187

Review 5.  Adherence to immunosuppressants: how can it be improved in adolescent organ transplant recipients?

Authors:  Emily M Fredericks; Dawn Dore-Stites
Journal:  Curr Opin Organ Transplant       Date:  2010-10       Impact factor: 2.640

Review 6.  The value of psychosocial factors in patient selection and outcomes after heart transplantation.

Authors:  Erin E Coglianese; Mekhala Samsi; Max J Liebo; Alain L Heroux
Journal:  Curr Heart Fail Rep       Date:  2015-02

Review 7.  Medical adherence and liver transplantation: a brief review.

Authors:  Carl Hammond; Trana Hussaini; Eric M Yoshida
Journal:  Can Liver J       Date:  2021-02-24

8.  Quality of life after liver transplantation for hepatitis C infection.

Authors:  Tracey Dudley; Dawn Chaplin; Collette Clifford; David John Mutimer
Journal:  Qual Life Res       Date:  2007-07-31       Impact factor: 4.147

Review 9.  Psychiatric aspects of organ transplantation in critical care.

Authors:  Andrea DiMartini; Catherine Crone; Marian Fireman; Mary Amanda Dew
Journal:  Crit Care Clin       Date:  2008-10       Impact factor: 3.598

Review 10.  Patient adherence to medical treatment: a review of reviews.

Authors:  Sandra van Dulmen; Emmy Sluijs; Liset van Dijk; Denise de Ridder; Rob Heerdink; Jozien Bensing
Journal:  BMC Health Serv Res       Date:  2007-04-17       Impact factor: 2.655

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