Literature DB >> 10999999

Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents.

R M Scarborough1, D D Gretler.   

Abstract

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Year:  2000        PMID： 10999999     DOI： 10.1021/jm000022w

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  10 in total

1.  Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics.

Authors:  Tsan Xiao; Junichi Takagi; Barry S Coller; Jia-Huai Wang; Timothy A Springer
Journal:  Nature       Date:  2004-09-19       Impact factor: 49.962

2.  Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening.

Authors:  Jieqing Zhu; Jianghai Zhu; Ana Negri; Davide Provasi; Marta Filizola; Barry S Coller; Timothy A Springer
Journal:  Blood       Date:  2010-08-02       Impact factor: 22.113

3.  Intact alphaIIbbeta3 integrin is extended after activation as measured by solution X-ray scattering and electron microscopy.

Authors:  Edward T Eng; Benoit J Smagghe; Thomas Walz; Timothy A Springer
Journal:  J Biol Chem       Date:  2011-08-09       Impact factor: 5.157

4.  The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187.

Authors:  Valery Leytin; Asuman Mutlu; Sergiy Mykhaylov; David J Allen; Armen V Gyulkhandanyan; John Freedman
Journal:  Haematologica       Date:  2009-12       Impact factor: 9.941

5.  A thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V.

Authors:  V Ramakrishnan; F DeGuzman; M Bao; S W Hall; L L Leung; D R Phillips
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

6.  A general chemical principle for creating closure-stabilizing integrin inhibitors.

Authors:  Fu-Yang Lin; Jing Li; Yonghua Xie; Jianghai Zhu; Thi Thu Huong Nguyen; Yonghui Zhang; Jieqing Zhu; Timothy A Springer
Journal:  Cell       Date:  2022-09-15       Impact factor: 66.850

7.  Volatile anesthetics, not intravenous anesthetic propofol bind to and attenuate the activation of platelet receptor integrin αIIbβ3.

Authors:  Koichi Yuki; Weiming Bu; Motomu Shimaoka; Roderic Eckenhoff
Journal:  PLoS One       Date:  2013-04-03       Impact factor: 3.240

8.  Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3.

Authors:  Timothy A Springer; Jianghai Zhu; Tsan Xiao
Journal:  J Cell Biol       Date:  2008-08-18       Impact factor: 10.539

9.  RP-HPLC Method Development and Validation for Determination of Eptifibatide Acetate in Bulk Drug Substance and Pharmaceutical Dosage Forms.

Authors:  Maryam Bavand Savadkouhi; Hossein Vahidi; Abdul Majid Ayatollahi; Shirin Hooshfar; Farzad Kobarfard
Journal:  Iran J Pharm Res       Date:  2017       Impact factor: 1.696

Review 10.  Computational Modeling as a Tool to Investigate PPI: From Drug Design to Tissue Engineering.

Authors:  Juan J Perez; Roman A Perez; Alberto Perez
Journal:  Front Mol Biosci       Date:  2021-05-20
  10 in total

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