| Literature DB >> 10990436 |
C E Davis1, B C Duffy, R M Coates.
Abstract
[reaction: see text]The structure and relative stereochemistry of the novel silphiperfolane-type sesquiterpene cameroonan-7alpha-ol (1) were confirmed by a total synthesis of (+/-)-1 from 3,3,5-trimethylbicyclo[3.3.0]oct-1(8)-en-2-one (6) by means of a Sakurai reaction with (Z)-crotylsilane, free radical hydrobromination, base-induced cyclization, and LiAlH4 reduction.Entities:
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Year: 2000 PMID： 10990436 DOI： 10.1021/ol0063149
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005