Literature DB >> 10984462

The interactions between clinical informatics and bioinformatics: a case study.

R B Altman1.   

Abstract

For the past decade, Stanford Medical Informatics has combined clinical informatics and bioinformatics research and training in an explicit way. The interest in applying informatics techniques to both clinical problems and problems in basic science can be traced to the Dendral project in the 1960s. Having bioinformatics and clinical informatics in the same academic unit is still somewhat unusual and can lead to clashes of clinical and basic science cultures. Nevertheless, the benefits of this organization have recently become clear, as the landscape of academic medicine in the next decades has begun to emerge. The author provides examples of technology transfer between clinical informatics and bioinformatics that illustrate how they complement each other.

Mesh:

Year:  2000        PMID: 10984462      PMCID: PMC79038          DOI: 10.1136/jamia.2000.0070439

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  14 in total

1.  Probabilistic diagnosis using a reformulation of the INTERNIST-1/QMR knowledge base. I. The probabilistic model and inference algorithms.

Authors:  M A Shwe; B Middleton; D E Heckerman; M Henrion; E J Horvitz; H P Lehmann; G F Cooper
Journal:  Methods Inf Med       Date:  1991-10       Impact factor: 2.176

2.  Probabilistic diagnosis using a reformulation of the INTERNIST-1/QMR knowledge base. II. Evaluation of diagnostic performance.

Authors:  B Middleton; M A Shwe; D E Heckerman; M Henrion; E J Horvitz; H P Lehmann; G F Cooper
Journal:  Methods Inf Med       Date:  1991-10       Impact factor: 2.176

3.  Algorithms for Bayesian belief-network precomputation.

Authors:  E H Herskovits; G F Cooper
Journal:  Methods Inf Med       Date:  1991-04       Impact factor: 2.176

4.  A curriculum for bioinformatics: the time is ripe.

Authors:  R B Altman
Journal:  Bioinformatics       Date:  1998       Impact factor: 6.937

5.  Standardized representations of the literature: combining diverse sources of ribosomal data.

Authors:  R B Altman; N F Abernethy; R O Chen
Journal:  Proc Int Conf Intell Syst Mol Biol       Date:  1997

6.  RIBOWEB: linking structural computations to a knowledge base of published experimental data.

Authors:  R O Chen; R Felciano; R B Altman
Journal:  Proc Int Conf Intell Syst Mol Biol       Date:  1997

Review 7.  New strategies for the determination of macromolecular structure in solution.

Authors:  R B Altman; O Jardetzky
Journal:  J Biochem       Date:  1986-12       Impact factor: 3.387

8.  The treatment advice of a computer-based cancer chemotherapy protocol advisor.

Authors:  D H Hickam; E H Shortliffe; M B Bischoff; A C Scott; C D Jacobs
Journal:  Ann Intern Med       Date:  1985-12       Impact factor: 25.391

9.  Ontology-based configuration of problem-solving methods and generation of knowledge-acquisition tools: application of PROTEGE-II to protocol-based decision support.

Authors:  S W Tu; H Eriksson; J H Gennari; Y Shahar; M A Musen
Journal:  Artif Intell Med       Date:  1995-06       Impact factor: 5.326

10.  Heuristic refinement method for the derivation of protein solution structures: validation on cytochrome b562.

Authors:  J F Brinkley; R B Altman; B S Duncan; B G Buchanan; O Jardetzky
Journal:  J Chem Inf Comput Sci       Date:  1988-11
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  7 in total

1.  The challenge of bridging between disciplines.

Authors:  W W Stead
Journal:  J Am Med Inform Assoc       Date:  2001 Jan-Feb       Impact factor: 4.497

2.  Bioinformatics and medical informatics: collaborations on the road to genomic medicine?

Authors:  Victor Maojo; Casimir A Kulikowski
Journal:  J Am Med Inform Assoc       Date:  2003-08-04       Impact factor: 4.497

3.  Variation of SNOMED CT coding of clinical research concepts among coding experts.

Authors:  James E Andrews; Rachel L Richesson; Jeffrey Krischer
Journal:  J Am Med Inform Assoc       Date:  2007-04-25       Impact factor: 4.497

Review 4.  Bioinformatics and cancer research: building bridges for translational research.

Authors:  Gonzalo Gómez-López; Alfonso Valencia
Journal:  Clin Transl Oncol       Date:  2008-02       Impact factor: 3.405

5.  UMLS-Query: a perl module for querying the UMLS.

Authors:  Nigam H Shah; Nigam Shah; Mark A Muse; Mark Musen
Journal:  AMIA Annu Symp Proc       Date:  2008-11-06

6.  A curricula-based comparison of biomedical and health informatics programs in the USA.

Authors:  Julia Kampov-Polevoi; Bradley M Hemminger
Journal:  J Am Med Inform Assoc       Date:  2011-02-02       Impact factor: 4.497

Review 7.  Biomedical informatics and translational medicine.

Authors:  Indra Neil Sarkar
Journal:  J Transl Med       Date:  2010-02-26       Impact factor: 5.531

  7 in total

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