| Literature DB >> 10977091 |
Abstract
The first available genome of a multicellular organism, C. elegans, was used as a test case for protein fold assignment using PSI-BLAST, followed by rational structure modeling and interpretation of experimental mutagenesis data in the context of collaboration with biologists. Similar results are demonstrated for human disease proteins with known polymorphisms.Entities:
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Year: 2000 PMID： 10977091
Source DB: PubMed Journal: Proc Int Conf Intell Syst Mol Biol ISSN： 1553-0833