Literature DB >> 10973240

A putative pheromone receptor gene expressed in human olfactory mucosa.

I Rodriguez1, C A Greer, M Y Mok, P Mombaerts.   

Abstract

Pheromones elicit specific behavioural responses and physiological alterations in recipients of the same species. In mammals, these chemical signals are recognized within the nasal cavity by sensory neurons that express pheromone receptors. In rodents, these receptors are thought to be represented by two large multigene families, comprising the V1r and V2r genes, which encode seven-transmembrane proteins. Although pheromonal effects have been demonstrated in humans, V1R or V2R counterparts of the rodent genes have yet to be characterized.

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Year:  2000        PMID: 10973240     DOI: 10.1038/79124

Source DB:  PubMed          Journal:  Nat Genet        ISSN: 1061-4036            Impact factor:   38.330


  48 in total

1.  Sequence analysis of mouse vomeronasal receptor gene clusters reveals common promoter motifs and a history of recent expansion.

Authors:  Robert P Lane; Tyler Cutforth; Richard Axel; Leroy Hood; Barbara J Trask
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-18       Impact factor: 11.205

2.  Relaxed selective pressure on an essential component of pheromone transduction in primate evolution.

Authors:  Emily R Liman; Hideki Innan
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-11       Impact factor: 11.205

Review 3.  [The human vomeronasal organ].

Authors:  M Knecht; M Witt; N Abolmaali; K B Hüttenbrink; T Hummel
Journal:  Nervenarzt       Date:  2003-10       Impact factor: 1.214

Review 4.  Use it or lose it: molecular evolution of sensory signaling in primates.

Authors:  Emily R Liman
Journal:  Pflugers Arch       Date:  2006-08-03       Impact factor: 3.657

Review 5.  Sex and the nose: human pheromonal responses.

Authors:  Mahmood F Bhutta
Journal:  J R Soc Med       Date:  2007-06       Impact factor: 5.344

Review 6.  Are pheromones detected through the main olfactory epithelium?

Authors:  Zhenshan Wang; Aaron Nudelman; Daniel R Storm
Journal:  Mol Neurobiol       Date:  2007-06       Impact factor: 5.590

Review 7.  The combined role of the main olfactory and vomeronasal systems in social communication in mammals.

Authors:  Kevin R Kelliher
Journal:  Horm Behav       Date:  2007-09-04       Impact factor: 3.587

8.  Pheromone signal transduction in humans: what can be learned from olfactory loss.

Authors:  Ivanka Savic; Ebba Hedén-Blomqvist; Hans Berglund
Journal:  Hum Brain Mapp       Date:  2009-09       Impact factor: 5.038

9.  Extreme variability among mammalian V1R gene families.

Authors:  Janet M Young; Hillary F Massa; Li Hsu; Barbara J Trask
Journal:  Genome Res       Date:  2009-12-01       Impact factor: 9.043

10.  Mammalian olfactory receptors.

Authors:  Joerg Fleischer; Heinz Breer; Joerg Strotmann
Journal:  Front Cell Neurosci       Date:  2009-08-27       Impact factor: 5.505

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