Literature DB >> 109707

Transfer RNA in aging Drosophila: II. Isoacceptor patterns.

H A Hosbach, E Kubli.   

Abstract

Transfer RNA and aminoacyl-tRNA synthetases have been isolated from 5 and 35 day old Drosophila melanogaster males. The isoacceptor pattern of the following tRNAs is not changed irrespective of the source of the tRNA and amino-acylating enzymes: tRNAAla, tRNALeu, tRNAMet, and tRNASer. However, the Q base containing tRNAAsp, tRNAAsN, tRNAHis, and tRNATyr show dramatic changes in their isoacceptor patterns during the aging process. This probably reflects a change in the activity of a tRNA modifying enzyme. These findings are discussed in relation to Strehler's theory of aging and development.

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Year:  1979        PMID： 109707     DOI： 10.1016/0047-6374(79)90077-0

Source DB:  PubMed          Journal:  Mech Ageing Dev        ISSN： 0047-6374            Impact factor:   5.432


  12 in total

1.  The nucleotide sequence of phenylalanine tRNA2 of Drosophila melanogaster: four isoacceptors with one basic sequence.

Authors:  M Altwegg; E Kubli
Journal:  Nucleic Acids Res       Date:  1979-09-11       Impact factor: 16.971

Review 2.  Eucaryotic codes.

Authors:  F Caron
Journal:  Experientia       Date:  1990-12-01

3.  On the possible role of tRNA base modifications in the evolution of codon usage: queuosine and Drosophila.

Authors:  Ylenia Chiari; Kirstin Dion; James Colborn; Aristeidis Parmakelis; Jeffrey R Powell
Journal:  J Mol Evol       Date:  2010-03-24       Impact factor: 2.395

4.  Temperature mediated variation of DNA secondary structure in (A.T) clusters; evidence by use of the oligopeptide netropsin as a structural probe.

Authors:  K E Reinert; D Geller; E Stutter
Journal:  Nucleic Acids Res       Date:  1981-05-25       Impact factor: 16.971

5.  The localization of tRNAAsp2 genes from Drosophila melanogaster by "in situ" hybridization.

Authors:  T Schmidt; A H Egg; E Kubli
Journal:  Mol Gen Genet       Date:  1978-09-08

6.  tRNAHis 5-methylcytidine levels increase in response to several growth arrest conditions in Saccharomyces cerevisiae.

Authors:  Melanie A Preston; Sonia D'Silva; Yoshiko Kon; Eric M Phizicky
Journal:  RNA       Date:  2012-12-18       Impact factor: 4.942

7.  Analysis of a shift in codon usage in Drosophila.

Authors:  Jeffrey R Powell; Erminia Sezzi; Etsuko N Moriyama; Jennifer M Gleason; Adalgisa Caccone
Journal:  J Mol Evol       Date:  2003       Impact factor: 2.395

8.  Presence of queuine in Drosophila melanogaster: correlation of free pool with queuosine content of tRNA and effect of mutations in pteridine metabolism.

Authors:  K B Jacobson; W R Farkas; J R Katze
Journal:  Nucleic Acids Res       Date:  1981-05-25       Impact factor: 16.971

9.  The localization of tRNA5Asn, tRNAHis, and tRNAAla genes from drosophila melanogaster by in situ hybridization to polytene salivary gland chromosomes.

Authors:  T Schmidt; E Kubli
Journal:  Chromosoma       Date:  1980       Impact factor: 4.316

10.  The nucleotide sequence of histidine tRNA gamma of Drosophila melanogaster.

Authors:  M Altwegg; E Kubli
Journal:  Nucleic Acids Res       Date:  1980-08-11       Impact factor: 16.971
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