Literature DB >> 10967327

Recent developments and future directions in computational genomics.

S Tsoka1, C A Ouzounis.   

Abstract

Computational genomics is a subfield of computational biology that deals with the analysis of entire genome sequences. Transcending the boundaries of classical sequence analysis, computational genomics exploits the inherent properties of entire genomes by modelling them as systems. We review recent developments in the field, discuss in some detail a number of novel approaches that take into account the genomic context and argue that progress will be made by novel knowledge representation and simulation technologies.

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Year:  2000        PMID： 10967327     DOI： 10.1016/s0014-5793(00)01776-2

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  18 in total

1.  An efficient algorithm for large-scale detection of protein families.

Authors:  A J Enright; S Van Dongen; C A Ouzounis
Journal:  Nucleic Acids Res       Date:  2002-04-01       Impact factor: 16.971

Review 2.  Science, medicine, and the future: Bioinformatics.

Authors:  Ardeshir Bayat
Journal:  BMJ       Date:  2002-04-27

3.  The phylogenetic extent of metabolic enzymes and pathways.

Authors:  José Manuel Peregrin-Alvarez; Sophia Tsoka; Christos A Ouzounis
Journal:  Genome Res       Date:  2003-03       Impact factor: 9.043

4.  PipeOnline 2.0: automated EST processing and functional data sorting.

Authors:  Patricia Ayoubi; Xiaojing Jin; Saul Leite; Xianghui Liu; Jeson Martajaja; Abdurashid Abduraham; Qiaolan Wan; Wei Yan; Eduardo Misawa; Rolf A Prade
Journal:  Nucleic Acids Res       Date:  2002-11-01       Impact factor: 16.971

5.  Genome evolution reveals biochemical networks and functional modules.

Authors:  Christian von Mering; Evgeny M Zdobnov; Sophia Tsoka; Francesca D Ciccarelli; Jose B Pereira-Leal; Christos A Ouzounis; Peer Bork
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-12       Impact factor: 11.205

6.  Dictionary-driven protein annotation.

Authors:  Isidore Rigoutsos; Tien Huynh; Aris Floratos; Laxmi Parida; Daniel Platt
Journal:  Nucleic Acids Res       Date:  2002-09-01       Impact factor: 16.971

7.  Automated metabolic reconstruction for Methanococcus jannaschii.

Authors:  Sophia Tsoka; David Simon; Christos A Ouzounis
Journal:  Archaea       Date:  2004-10       Impact factor: 3.273

8.  Analysis of microarray experiments of gene expression profiling.

Authors:  Adi L Tarca; Roberto Romero; Sorin Draghici
Journal:  Am J Obstet Gynecol       Date:  2006-08       Impact factor: 8.661

9.  Coverage of whole proteome by structural genomics observed through protein homology modeling database.

Authors:  Kei Yura; Akihiro Yamaguchi; Mitiko Go
Journal:  J Struct Funct Genomics       Date:  2006-12-05

10.  Visualizing sequence similarity of protein families.

Authors:  Vamsi Veeramachaneni; Wojciech Makałowski
Journal:  Genome Res       Date:  2004-05-12       Impact factor: 9.043
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